Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tadazumi Komiyama"'
Autor:
Habib Abul Muntasir, Murad Hossain, Mohiuddin Ahmed Bhuiyan, Tadazumi Komiyama, Takashi Nakamura, Masanobu Ozaki, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 3, Pp 274-277 (2007)
Based on radio-ligand binding and molecular modeling studies, sarpogrelate shows a moderate selectivity for 5-HT2B versus 5-HT2A receptors. To confirm the modeling data of sarpogrelate to 5-HT2B receptors predicting interaction of sarpogrelate toward
Externí odkaz:
https://doaj.org/article/ea6f7292e4fd4e53a7f7516a8e6c17ce
Autor:
Maruf Ahmed, Habib Abul Muntasir, Murad Hossain, Masaji Ishiguro, Tadazumi Komiyama, Ikunobu Muramatsu, Hitoshi Kurose, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 167-172 (2006)
We obtained a new mutant of the β1-adrenergic receptor (β1-AR) by point mutations that can constitutively activate β1-AR. Aspartate104 of the β1-AR in the 2nd transmembrane was replaced with alanine. The β1-AR mutant expressed in human embryonic
Externí odkaz:
https://doaj.org/article/3d634c84f06347f5abb44f6077455725
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 1, Pp 55-63 (2006)
The purpose of the present study was to examine 5-hydroxytryptamine (5-HT)2A-receptor sarpogrelate interactions by site-directed mutagenesis. Based on molecular modeling studies, aspartic acid (Asp)155[3.32] and tryptophan (Trp)151[3.28] in transmemb
Externí odkaz:
https://doaj.org/article/ce111e66bd294ef69ae4f21f741d38ca
Autor:
Takafumi Nagatomo, Ikunobu Muramatsu, Maruf Ahmed, Murad Hossain, Habib Abul Muntasir, Hitoshi Kurose, Masaji Ishiguro, Tadazumi Komiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 167-172 (2006)
We obtained a new mutant of the β1-adrenergic receptor (β1-AR) by point mutations that can constitutively activate β1-AR. Aspartate104 of the β1-AR in the 2nd transmembrane was replaced with alanine. The β1-AR mutant expressed in human embryonic
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 1, Pp 55-63 (2006)
The purpose of the present study was to examine 5-hydroxytryptamine (5-HT)2A-receptor sarpogrelate interactions by site-directed mutagenesis. Based on molecular modeling studies, aspartic acid (Asp)155[3.32] and tryptophan (Trp)151[3.28] in transmemb