Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Motohiro Nishida"'
Autor:
Yuri Kato, Kazuhiro Nishiyama, Akiyuki Nishimura, Takamasa Noda, Kaori Okabe, Takahiro Kusakabe, Yasunari Kanda, Motohiro Nishida
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 108-114 (2022)
Coronavirus disease 2019 (COVID-19) remains prevalent worldwide since its onset was confirmed in Wuhan, China in 2019. Vaccines against the causative virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have shown a preventive effect
Externí odkaz:
https://doaj.org/article/3dd9e49aa9634722aa390664711b16d1
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 139-146 (2022)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread and led to global health crises. COVID-19 causes well-known respiratory failure and gastrointestinal symptoms, such as dia
Externí odkaz:
https://doaj.org/article/c5c358d5e3c4435287d4a0a447a86784
Publikováno v:
Journal of Pharmacological Sciences, Vol 138, Iss 3, Pp 184-191 (2018)
Insulin resistance is a condition in which there is a defect in insulin actions to induce glucose uptake into the cells. Overstimulation of β2-adrenergic receptors (β2ARs) is associated with the pathogenesis of insulin resistance in the heart. Howe
Externí odkaz:
https://doaj.org/article/e901bb5d77ae4f0b8a13f8f160f51014
Autor:
Yu Guan, Daisuke Nakano, Yifan Zhang, Lei Li, Wenhua Liu, Motohiro Nishida, Takashige Kuwabara, Asahiro Morishita, Hirofumi Hitomi, Kiyoshi Mori, Masashi Mukoyama, Tsutomu Masaki, Katsuya Hirano, Akira Nishiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 135, Iss 2, Pp 81-88 (2017)
The kidney expresses protease-activated receptor-1 (PAR-1). PAR-1 is known as a thrombin receptor, but its role in kidney injury is not well understood. In this study, we examined the contribution of PAR-1 to kidney glomerular injury and the effects
Externí odkaz:
https://doaj.org/article/3b5c7f6a0f0a47dea29a51eac32c7642
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 3, Pp 336-345 (2011)
We revealed that pre-treatment with docetaxel (DOC) 12 h before adriamycin (ADR) administration significantly reduced ADR-induced toxic death compared with the simultaneous dosing schedule that was commonly used in previous studies. We considered tha
Externí odkaz:
https://doaj.org/article/34d2fac0d8694cc09d4ac980939b4b5d
Autor:
Motohiro Nishida
Publikováno v:
Journal of Pharmacological Sciences, Vol 117, Iss 1, Pp 1-5 (2011)
Abstract.: Heart failure is a major cause of death in developed countries, and the development of an epoch-making cure is desired from the viewpoint for improving the quality of life and reducing the medical cost of the patient. The importance of neu
Externí odkaz:
https://doaj.org/article/36e4cde4d7094ea8975001c9d0858c39
Dual Signaling Pathways of Arterial Constriction by Extracellular Uridine 5′-Triphosphate in the Rat
Autor:
Megumi Sugihara, Hiromitsu Morita, Miho Matsuda, Hisanori Umebayashi, Shunichi Kajioka, Shinichi Ito, Motohiro Nishida, Ryosuke Inoue, Toshiko Futatsuki, Jun Yamazaki, Yasuo Mori, Ryuji Inoue, Yushi Ito, Kihachiro Abe, Masato Hirata
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 3, Pp 293-308 (2011)
We investigated actions of uridine 5′-triphosphate (UTP) in rat aorta, cerebral and mesenteric arteries, and their single myocytes. UTP (≥10 μM) elicited an inward-rectifying current strongly reminiscent of activation of P2X1 receptor, and a sim
Externí odkaz:
https://doaj.org/article/6813dc7948864d5abeff809f6fccfe2d
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 2, Pp 168-174 (2005)
Cardiomyocytes express both β1- and β2-adrenergic receptors, and these receptors play a differential role in chronotropic and inotropic effects of the heart. Caveolae are known as an important regulator of G-protein-coupled receptor signaling. In t
Externí odkaz:
https://doaj.org/article/f4f27a33bc554b64a79d91d1f1b3668a
Publikováno v:
Journal of Pharmacological Sciences, Vol 138, Iss 3, Pp 184-191 (2018)
Insulin resistance is a condition in which there is a defect in insulin actions to induce glucose uptake into the cells. Overstimulation of β2-adrenergic receptors (β2ARs) is associated with the pathogenesis of insulin resistance in the heart. Howe
Autor:
Akira Nishiyama, Katsuya Hirano, Asahiro Morishita, Motohiro Nishida, Kiyoshi Mori, Lei Li, Hirofumi Hitomi, Takashige Kuwabara, Tsutomu Masaki, Masashi Mukoyama, Wenhua Liu, Yu Guan, Yifan Zhang, Daisuke Nakano
Publikováno v:
Journal of Pharmacological Sciences, Vol 135, Iss 2, Pp 81-88 (2017)
The kidney expresses protease-activated receptor-1 (PAR-1). PAR-1 is known as a thrombin receptor, but its role in kidney injury is not well understood. In this study, we examined the contribution of PAR-1 to kidney glomerular injury and the effects