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Autor:
Rishi Deka, David D. Stenehjem, Vanessa Stevens, Marisa B. Schauerhamer, Sudhir Unni, Ancilla W. Fernandes, Diana I. Brixner, Jerzy E. Tyczynski
Publikováno v:
Journal of Ovarian Research
Background Breast cancer associated (BRCA) genes are critical for DNA repair. Mutations in BRCA1 and BRCA2 (BRCAm) result in loss of these repair mechanisms and potential carcinogenesis. Germline BRCAm are common in ovarian carcinomas, particularly i