Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mauro Alini"'
Publikováno v:
Journal of Orthopaedic Translation, Vol 38, Iss , Pp 106-116 (2023)
Background: Osteoarthritis (OA) is the most common degenerative joint disease, mainly affecting the elderly worldwide, for which the drug treatment remains a major challenge. Low-grade inflammation plays a pivotal role in OA onset and progression. Ex
Externí odkaz:
https://doaj.org/article/3b8eaf88ff934dbbb4ffa0b7e683e6fe
Publikováno v:
Journal of Orthopaedic Translation, Vol 26, Iss , Pp 101-110 (2021)
Background: Osteochondral defects (OCD) are common in osteoarthritis (OA) and difficult to heal. Numerous tissue engineering approaches and novel biomaterials are developed to solve this challenging condition. Although most of the novel methods can s
Externí odkaz:
https://doaj.org/article/4b4f1705274544c4a2f07d4bb0121454
One strike loading organ culture model to investigate the post-traumatic disc degenerative condition
Publikováno v:
Journal of Orthopaedic Translation, Vol 26, Iss , Pp 141-150 (2021)
Summary: Background: Acute trauma on intervertebral discs (IVDs) is thought to be one of the risk factors for IVD degeneration. The pathophysiology of IVD degeneration induced by single high impact mechanical injury is not very well understood. The a
Externí odkaz:
https://doaj.org/article/1decff6ace284ab8b47e6062d4a3f5f6
Autor:
Marianna Peroglio, Luzia Simone Douma, Tansinee Stephanie Caprez, Milena Janki, Lorin Michael Benneker, Mauro Alini, Sibylle Grad
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 43-51 (2017)
In vitro and in vivo studies evidenced that mesenchymal stem cells (MSCs) contribute to intervertebral disc (IVD) regeneration by differentiation towards the disc phenotype and matrix synthesis and/or by paracrine signalling to endogenous cells, ther
Externí odkaz:
https://doaj.org/article/58a18f6956be416893261bcd79d72559
Autor:
Dalila Petta, Garland Fussell, Lisa Hughes, Douglas D. Buechter, Christoph M. Sprecher, Mauro Alini, David Eglin, Matteo D'Este
Publikováno v:
Journal of Orthopaedic Translation, Vol 5, Iss C, Pp 57-68 (2016)
Background/Objective: Advanced synthetic biomaterials that are able to reduce or replace the need for autologous bone transplantation are still a major clinical need in orthopaedics, dentistry, and trauma. Key requirements for improved bone substitut
Externí odkaz:
https://doaj.org/article/d44a90f4b1024232afd8ff4a8459324b
Autor:
David Eglin, Mauro Alini, Joost de Bruijn, Julien Gautrot, Dirk W. Grijpma, Lukas Kamer, Yuxiao Lai, Shibi Lu, Ton Peijs, Jian Peng, Ting Ting Tang, Xianluan Wang, Xinjiang Wang, R. Geoff Richards, Ling Qin
Publikováno v:
Journal of Orthopaedic Translation, Vol 3, Iss 2, Pp 78-84 (2015)
The research project entitled “rapid prototyping of custom-made bone-forming tissue engineering constructs” (RAPIDOS) is one of the three unique projects that are the result of the first coordinated call for research proposals in biomaterials lau
Externí odkaz:
https://doaj.org/article/781c6bec7f1c430f94cec0f69eb79d82
Publikováno v:
Journal of Orthopaedic Translation, Vol 26, Iss, Pp 101-110 (2021)
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation
Background Osteochondral defects (OCD) are common in osteoarthritis (OA) and difficult to heal. Numerous tissue engineering approaches and novel biomaterials are developed to solve this challenging condition. Although most of the novel methods can su
One strike loading organ culture model to investigate the post-traumatic disc degenerative condition
Publikováno v:
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation, Vol 26, Iss, Pp 141-150 (2021)
Journal of Orthopaedic Translation, Vol 26, Iss, Pp 141-150 (2021)
Summary: Background: Acute trauma on intervertebral discs (IVDs) is thought to be one of the risk factors for IVD degeneration. The pathophysiology of IVD degeneration induced by single high impact mechanical injury is not very well understood. The a
Autor:
Luzia Simone Douma, Marianna Peroglio, Mauro Alini, Lorin Michael Benneker, Sibylle Grad, Milena Janki, Tansinee Stephanie Caprez
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 43-51 (2017)
Peroglio, Marianna; Douma, Luzia Simone; Caprez, Tansinee Stephanie; Janki, Milena; Benneker, Lorin Michael; Alini, Mauro; Grad, Sibylle (2017). Intervertebral disc response to stem cell treatment is conditioned by disc state and cell carrier: An ex vivo study. Journal of orthopaedic translation, 9, pp. 43-51. Elsevier 10.1016/j.jot.2017.03.003
Journal of Orthopaedic Translation
Peroglio, Marianna; Douma, Luzia Simone; Caprez, Tansinee Stephanie; Janki, Milena; Benneker, Lorin Michael; Alini, Mauro; Grad, Sibylle (2017). Intervertebral disc response to stem cell treatment is conditioned by disc state and cell carrier: An ex vivo study. Journal of orthopaedic translation, 9, pp. 43-51. Elsevier 10.1016/j.jot.2017.03.003
Journal of Orthopaedic Translation
Summary In vitro and in vivo studies evidenced that mesenchymal stem cells (MSCs) contribute to intervertebral disc (IVD) regeneration by differentiation towards the disc phenotype and matrix synthesis and/or by paracrine signalling to endogenous cel
Autor:
K. Kluge, Dirk W. Grijpma, Geoff Richards, Ursula Eberli, David Eglin, Mike A. Geven, Olivier Guillaume, Mauro Alini, Stephan Zeiter
Publikováno v:
Journal of Orthopaedic Translation, Vol 7, Iss C, p 80 (2016)