Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mauro Alini"'
Autor:
Vincenzo Denaro, Giuseppina Catanzaro, Mauro Alini, Matteo D'Este, Lorenza Lazzari, Caterina Cattani, Fabrizio Russo, Gianluca Vadalà, Rosaria Giordano, Maria Cristina Tirindelli, Maria Letizia Musumeci
Publikováno v:
Journal of Orthopaedic Research. 35:2109-2116
Intervertebral disc regeneration is quickly moving towards clinical applications. However, it is still missing an ideal injectable hydrogel to support mesenchymal stem cells (MSC) delivery. Herein, a new injectable hydrogel composed of platelet rich
Autor:
Tomoko Nakai, Mauro Alini, Kiyoshi Ando, Tadashi Nukaga, Zhen Li, Koichi Masuda, Joji Mochida, Masahiko Watanabe, Sibylle Grad, Daisuke Sakai, Daniel W. Chan, Yoshihiko Nakamura
Publikováno v:
Journal of Orthopaedic Research. 34:1361-1372
Characterization of cells is important for facilitating cell-based therapies for degenerative diseases of intervertebral discs. For this purpose, we analyzed mouse annulus fibrosus cells by flowcytometory to detect phenotypic change in their primary
Autor:
Zhen Li, Sibylle Grad, Franz E. Weber, Lindsay S. Karfeld-Sulzer, R. Geoff Richards, Gernot Lang, Mauro Alini, Avner Yayon, Hagit Sacks, Chris Sammon, Kerstin T. Mader
Publikováno v:
Journal of Orthopaedic Research. 35:51-60
Intervertebral disc (IVD) degeneration is the leading trigger of low back pain, which causes disability and leads to enormous healthcare toll worldwide. Biological treatment with growth factors has evolved as potential therapy for IVD regeneration. B
Publikováno v:
Journal of Orthopaedic Research.
Articular cartilage is a load-bearing tissue playing a crucial mechanical role in diarthrodial joints, facilitating joint articulation, and minimizing wear. The significance of biomechanical stimuli in the development of cartilage and maintenance of
Publikováno v:
Journal of Orthopaedic Research.
The purpose of this review is to provide a brief overview of bioreactor-based culture systems as alternatives to conventional two- and three-dimensional counterparts. The role, challenges, and future aspirations of bioreactors in the musculoskeletal
Publikováno v:
Journal of Orthopaedic Research. 26:579-588
Kinetics of mRNA expression following a single loading event was measured using an in vivo rat tail model. Animals were instrumented and loaded in compression for 1.5 h at 1 MPa and 1 Hz. Real-time RT-PCR was used to measure mRNA levels 0, 8, 24 and
Publikováno v:
Journal of Orthopaedic Research. 23:1120-1127
The goal of this study was to determine the time-dependent response of the intervertebral disc cells to in vivo dynamic compression. Forty-seven skeletally mature Wistar rats (>12 months old) were instrumented with an Ilizarov-type device spanning ca