Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Homira Behbahani"'
Publikováno v:
Journal of Neuroscience Research. 84:596-605
PTEN is a dual phosphatase that negatively regulates the phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway important for cell survival. We determined effects of the inflammation and oxidative stresses of tumor necrosis factor-alpha (TNFalph
Autor:
Birgitta Wiehager, Bengt Winblad, Hernan Concha, Richard F. Cowburn, Maria Ankarcrona, Kjell Hultenby, Homira Behbahani, Jan Nedergaard, Irina G. Shabalina, Natasa Petrovic
Publikováno v:
Journal of neuroscience research. 84(4)
Increasing evidence indicates that mitochondrial alterations contribute to the neuronal death in Alzheimer's disease (AD). Presenilin 1 (PS1) and Presenilin 2 (PS2) mutations have been shown to sensitize cells to apoptosis by mechanisms suggested to
Autor:
Hernan Concha, Annika Rickle, Homira Behbahani, Bengt Winblad, Richard F. Cowburn, Maria Ankarcrona
Publikováno v:
Journal of neuroscience research. 82(3)
The mechanisms associated with cell death have been an important focus for neurobiology research. In the present study, the methodology of flow cytometry was used to optimize quantification of the toxic effects of tumor necrosis factor-alpha (TNF-alp