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Autor:
Bálint Lasztóczi, Julianna Kardos
Publikováno v:
Journal of Neurophysiology. 96:3538-3544
Here we address the effects of cyclothiazide (CTZ), an allosteric inhibitor of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor desensitization, on low [Mg2+]–induced seizure-like events (SLEs) recorded from the CA3 pyramidal
Autor:
Donald A. Simone, Lisa M. Johanek
Publikováno v:
Journal of Neurophysiology. 93:989-997
Low doses of cannabinoids applied intrathecally attenuate capsaicin-evoked heat and mechanical hyperalgesia via CB1 receptors. Although cannabinoids produce antinociception, in part, by attenuating responses of nociceptive neurons in the spinal cord,
Autor:
J. A. Dani, Robin A. J. Lester
Publikováno v:
Journal of Neurophysiology. 74:195-206
1. The activation and desensitization properties of nicotinic acetylcholine receptor (nAChR) channels were examined in acutely isolated medial habenula (MHb) neurons using whole cell patch-clamp recordings. nAChR-mediated currents were evoked by appl
Publikováno v:
Journal of neurophysiology. 103(1)
The sphenopalatine ganglion (SPG) neurons represent the parasympathetic branch of the autonomic nervous system involved in controlling cerebral blood flow. In the present study, we examined the coupling mechanism between mu (μ) opioid receptors (MOR
Publikováno v:
Journal of neurophysiology. 102(2)
Hypophonia is an early symptom in Parkinson's disease (PD) that involves an increase in laryngeal muscle activity, interfering with voice production. Our aim was to use an animal model to better understand the role of different dopamine receptor subt
Publikováno v:
Journal of neurophysiology. 91(3)
The search for an endogenous ligand for the vanilloid receptor (VR or TRPV1) has led to the identification of N-arachidonyl dopamine (NADA). This study investigates the role of protein kinase C (PKC)-mediated phosphorylation on NADA-induced membrane
Autor:
Lieju Liu, Sidney A. Simon, Zhu-Shan Zhang, Weiguo Zhu, Gerry S. Oxford, Augustus O. Grant, Tainming Yang
Publikováno v:
Journal of neurophysiology. 91(4)
Nicotine is an alkaloid that is used by large numbers of people. When taken into the body, it produces a myriad of physiological actions that occur primarily through the activation of neuronal nicotinic acetylcholine receptors (nAChRs). We have explo
Publikováno v:
Journal of neurophysiology. 83(4)
Single-fiber recordings were made from the decentralized right cervical vagus nerve (hyponodosal) of the rat. A total of 56 afferent fibers that responded to gastric distension (GD) were studied: 6 fibers were stimulated by phasic balloon GD, 50 by f
Publikováno v:
Journal of neurophysiology. 81(4)
Functional GABAAreceptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. CA1 pyramidal cells were voltage clamped, and GABA was applied to individual cells with a modified U-tube, rapid drug application system. With Vh= −50 mV
Publikováno v:
Journal of neurophysiology. 72(3)
1. Our recent studies in rats have demonstrated that the small-fiber excitant and inflammatory irritant mustard oil injected into the temporomandibular joint (TMJ) region can evoke a sustained and reversible increase of electromyographic (EMG) activi