Zobrazeno 1 - 8
of 8
pro vyhledávání: ''
Autor:
Bálint Lasztóczi, Julianna Kardos
Publikováno v:
Journal of Neurophysiology. 96:3538-3544
Here we address the effects of cyclothiazide (CTZ), an allosteric inhibitor of α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor desensitization, on low [Mg2+]–induced seizure-like events (SLEs) recorded from the CA3 pyramidal
Autor:
Gregory O. Hjelmstad, Howard L. Fields
Publikováno v:
Journal of Neurophysiology. 85:1153-1158
Microinjection of kappa-opioid receptor agonists into the nucleus accumbens produces conditioned place aversion. While attention has focused primarily on the inhibition of dopamine release by kappa-receptor agonists as the synaptic mechanism underlyi
Autor:
Gregory L. Gerdeman, David M. Lovinger
Publikováno v:
Journal of Neurophysiology. 85:468-471
CB1 cannabinoid receptors in the neostriatum mediate profound motor deficits induced when cannabinoid drugs are administered to rodents. Because the CB1 receptor has been shown to inhibit neurotransmitter release in various brain areas, we investigat
Publikováno v:
Journal of neurophysiology. 105(1)
TNFα induces mechanical sensitization of rat masseter muscle nociceptors, which takes 2–3 h to manifest and is mediated through activation of P55 and P75 receptors. This study was undertaken to determine whether TNFα induces nociceptor mechanical
Autor:
Francesca Guida, Livio Luongo, Katarzyna Starowicz, Vito de Novellis, Sabatino Maione, Francesca Rossi, Enza Palazzo, Luigia Cristino, Ida Marabese, Vincenzo Di Marzo
Publikováno v:
Journal of neurophysiology. 101(5)
The transient receptor potential vanilloid-1 (TRPV1) receptor is involved in peripheral and spinal nociceptive processing and is a therapeutic target for pain. We have shown previously that TRPV1 in the ventrolateral periaqueductal gray (VL-PAG) toni
Publikováno v:
Journal of neurophysiology. 84(1)
Schizophrenia is considered to be associated with an abnormal functioning of the hippocampal output. The high clinical potency of antipsychotics that act as antagonists at dopamine (DA) receptors indicate a hyperfunction of the dopaminergic system. T
Autor:
Kuei Sen Hsu
Publikováno v:
Journal of neurophysiology. 76(3)
1. The effect of dopamine (DA) on the excitatory synaptic transmission was studied in the CA1 neurons of rat hippocampal slices using intracellular recording technique. 2. Depolarizing excitatory postsynaptic potentials (EPSPs) were evoked by stimula
Publikováno v:
Journal of neurophysiology. 75(6)
1. The kinetics of onset of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization by glutamate, and the extent of attenuation of AMPA receptor desensitization by cyclothiazide, showed pronounced cell-to-cell variati