Zobrazeno 1 - 9
of 9
pro vyhledávání: '"11"'
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 67:677-686
We previously identified immunocytochemical evidence of nitrative and oxidative injury in premyelinating oligodendrocytes in periventricular leukomalacia (PVL). Here, we tested the hypothesis that free radical injury occurs in the overlying cerebral
Autor:
Leah R. Anderson, Jeffrey R. Gulcher, Marla Gearing, Ranjita Betarbet, Kari Stefansson, James J. Lah, Andrew A. Hicks, Allan I. Levey
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 66:955-964
The PARK10 locus is associated with idiopathic Parkinson disease (PD), but the responsible gene remains to be identified. Genes associated with familial PD, as well as biochemical evidence from sporadic PD and animal models, have implicated component
Autor:
Torsten Pietsch, Rogier Versteeg, Marzia Perera, Wiesława Grajkowska, Peter van Sluis, Marcel Kool, Oliver Wirths, Giorgio Corte, Esmeralda Oussoren, Lorna Zadravec-Zaletel, Talitha de Haas, Dirk Troost, Frank Baas, Mara Popović, Marta Perek-Polnik
Publikováno v:
Journal of neuropathology and experimental neurology, 65(2), 176-186. Lippincott Williams and Wilkins
OTX1 and OTX2 are transcription factors with an essential role in the development of the cerebellum. We previously described a high OTX2 expression in medulloblastoma. Here, we analyzed amplification and mRNA expression of OTX1 and OTX2 in a series o
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 57:674-683
A characteristic feature of the parvopyramidal layer of the presubiculum of 6 individuals with Alzheimer disease (AD) was the presence of large, evenly distributed amyloid-beta (A beta) deposits, which in the end stage of the disease occupy 80.9 +/-
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 56:285-290
Activated microglia, overexpressing interleukin-1 (IL-1), and activated astrocytes, overexpressing S100beta, have been implicated in the formation and evolution of tau2-immunoreactive (tau2+) neuritic plaques in Alzheimer disease. In this study, we a
Autor:
Masaru Shimoda, Shinsuke Kato, Yasuhiro Watanabe, Kazuro Takahashi, Kenji Nakashima, Eisaku Ohama
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 55:1089-1101
We performed a comparative neuropathological study on two siblings with familial amyotrophic lateral sclerosis (FALS). The clinical course of the sister who died at age 46 was 18 months, and that of the brother who died at age 65, 11 years. The neuro
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 53:61-71
Cerebellar dysplasias are commonly found in the white matter and nodulus of the vermis in newborns and are particularly prominent in infants with trisomy 13-15 and trisomy 18 syndromes. Little is known of the developmental biology of these structures
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 46:239-249
Cell surface expression of Class II major histocompatibility complex (Ia) molecules is required for antigen recognition by T cells. To determine the ultrastructural cellular distribution of Ia molecules in the autoimmune disease model acute experimen
Autor:
Karl T. Neubuerger, Harry M. McCormick
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 17:471-478
Giant-cell arteritis (cranial, temporal or granulomatous arteritis) has been recognized for a quarter of a century. An entirely satisfactory name for the condition has not yet been found. The clinical picture in typical cases is characteristic. The v