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Autor:
Michael Swash
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 88:603-607
Clinical assessment of a patient presenting with a neuromuscular disorder follows a standardised path, hallowed by clinical practice. Symptomatic history, family history and physical examination are followed by the development of a plan for further i
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 86:1356-1361
Bell's palsy is a common cranial neuropathy causing acute unilateral lower motor neuron facial paralysis. Immune, infective and ischaemic mechanisms are all potential contributors to the development of Bell's palsy, but the precise cause remains uncl
Autor:
James Rooney, Orla Hardiman, Alison Dick, Mark Heverin, Colette Donaghy, Susan Byrne, Katy Tobin
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 86:496-501
Background Amyotrophic lateral sclerosis (ALS) is a progressive debilitating neurodegenerative disease, with a life expectancy of 3–5 years from first symptom. There is compelling evidence that those who attend a multidisciplinary clinic experience
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 86:635-639
Objective To develop and validate a reliable patient-reported scale that grades the severity of disability in Charcot-Marie-tooth disease (CMT), from an in-depth analysis of patient and healthcare provider perspectives on what mobility changes consti
Autor:
Catherine Williamson, Fiona Norwood, N. James, Mandish Dhanjal, Stephanie A. Robb, Geraldine O'Sullivan, Heinz Jungbluth, Jacqueline Palace, Pippa Kyle, David Hilton-Jones, Catherine Nelson-Piercy, Marguerite Hill
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 85:538-543
A national U.K. workshop to discuss practical clinical management issues related to pregnancy in women with myasthenia gravis was held in May 2011. The purpose was to develop recommendations to guide general neurologists and obstetricians and facilit
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 84:94-97
Background Intravenous immunoglobulin (IVIG) and plasmapheresis (plasma exchange (PLEX)) have comparable efficacy in reducing the Quantitative Myasthenia Gravis Score for disease severity (QMGS) in patients with moderate to severe myasthenia gravis (
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 82:839-842
Objective To evaluate the frequency, severity and determinants of sleep disturbances in patients with amyotrophic lateral sclerosis (ALS). Methods Information about night-time complaints was collected using a standardised questionnaire, the Pittsburg
Autor:
Girija Sadalage, Paul Maddison, Saiju Jacob, David Hilton-Jones, Camilla Buckley, Angela Vincent
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 88:A65.4-A66
There is an increasing incidence and prevalence of MG in older patients (>50 years) – defined as Late Onset Myasthenia Gravis (LOMG). This study aims to define the demographics, clinical features, response to treatment and immunological features wh
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 80:1146-1149
Background: Amyotrophic lateral sclerosis (ALS) patients report both fatigue and depression. It is not clear how frequently each occurs, to what extent they occur together, how each relates to ALS disease status, or their stability over time. Objecti
Publikováno v:
Journal of Neurology, Neurosurgery and Psychiatry, Vol. 81, no. 5, p. 506-512 (2010)
Neuromuscular disorders (NMDs) can lead to specific manual disabilities due to hand muscle weakness and atrophy, myotonia, or loss of sensory function. The aim of this study was to adapt and validate the ABILHAND questionnaire in children and adults