Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Goutam Chakraborty"'
Publikováno v:
Journal of Neurochemistry. 121:806-817
J. Neurochem. (2012) 121, 806–817. Abstract Our previous studies have indicated that de novo ceramide synthesis plays a critical role in ethanol-induced apoptotic neurodegeneration in the 7-day-old mouse brain. In this study, we examined whether th
Autor:
Mitsuo Saito, Kostantin Dobrenis, Rui Fen Mao, Goutam Chakraborty, R. D. Shah, Dun-Sheng Yang, Mariko Saito, Asok Kumar
Publikováno v:
Journal of Neurochemistry. 121:649-661
GM2 ganglioside in the brain increased during ethanol-induced acute apoptotic neurodegeneration in 7-day-old mice. A small but a significant increase observed 2 h after ethanol exposure was followed by a marked increase around 24 h. Subcellular fract
Autor:
Mariko Saito, Goutam Chakraborty, Medha Hegde, Sun-Mee Paik, Jason Ohsie, Mitsuo Saito, Csaba Vadasz
Publikováno v:
Journal of Neurochemistry. 115:168-177
Acute administration of ethanol to 7-day-old mice is known to cause robust apoptotic neurodegeneration in the brain. Our previous studies have shown that such ethanol-induced neurodegeneration is accompanied by increases in lipids, including ceramide
Publikováno v:
Journal of Neurochemistry. 78:736-745
Despite its growing use as a radiological indicator of neuronal viability, the biological function of N-acetylaspartate (NAA) has remained elusive. This is due in part to its unusual metabolic compartmentalization wherein the synthetic enzyme occurs
Publikováno v:
Journal of neurochemistry. 121(5)
Our previous studies have indicated that de novo ceramide synthesis plays a critical role in ethanol-induced apoptotic neurodegeneration in the 7-day-old mouse brain. In this study, we examined whether the formation of sphingosine 1-phosphate (S1P),
Autor:
Mariko, Saito, Goutam, Chakraborty, Medha, Hegde, Jason, Ohsie, Sun-Mee, Paik, Csaba, Vadasz, Mitsuo, Saito
Publikováno v:
Journal of neurochemistry. 115(1)
Acute administration of ethanol to 7-day-old mice is known to cause robust apoptotic neurodegeneration in the brain. Our previous studies have shown that such ethanol-induced neurodegeneration is accompanied by increases in lipids including ceramide,
Autor:
Mariko Saito, Mitsuo Saito, Ray Wang, Goutam Chakraborty, Thomas B. Cooper, Csaba Vadasz, Rui-Fen Mao
Publikováno v:
Journal of neurochemistry. 103(3)
Previously, we have shown that ethanol-induced apoptosis in cultured neurons is accompanied by changes in cellular lipid profiles. In the present study, the effects of ethanol on brain lipid metabolism were studied using 7-day-old C57BL/6ByJ mice, wh
Publikováno v:
Journal of Neurochemistry. 43:1286-1294
Experiments were performed to determine whether ppsttranslational addition of amino acids to axonal proteins occurs in axons of the rat sciatic nerve. Two ligatures were placed 1 cm apart on sciatic nerves. Six days later, segments proximal to each l