Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Danxin Wang"'
Publikováno v:
Journal of neurochemistry. 75(2)
Calmodulin (CaM) has been shown to suppress basal G protein coupling and attenuate agonist-stimulated G protein coupling of the mu-opioid receptor (OP(3)) through direct interaction with the third intracellular (i3) loop of the receptor. Here we have
Publikováno v:
Journal of neurochemistry. 74(4)
Previous evidence has suggested a role for calmodulin (CaM) in opioid receptor signaling. We demonstrate here that morphine stimulation of the μ-opioid (OP 3 ) receptor causes rapid CaM translocation to the nucleus in OP 3 -transfected human embryon