Zobrazeno 91 - 100
of 251
pro vyhledávání: ''
Publikováno v:
Journal of neurochemistry. 111(1)
We employed in vivo microdialysis to characterize the effect of an ethanol challenge injection on endocannabinoid levels in the nucleus accumbens of ethanol-naïve and chronic ethanol-treated rats. Ethanol (0.75 and 2 g/kg, i.p.) dose-dependently inc
Autor:
Toni L. Richards, Nancy R. Zahniser
Publikováno v:
Journal of neurochemistry. 108(6)
The neurotransmitter dopamine (DA) plays an essential role in normal CNS functions such as cognition, locomotion, and reward (Iversen and Iversen 2007). The duration and extent of DA neurotransmission is largely limited by DA transporters (DATs) (Jab
Publikováno v:
Journal of Neurochemistry. 57:1878-1883
Experiments examined the effects of peripheral and central administration of the vesicular acetylcholine transport blocker vesamicol (AH5183) on the content, synthesis, and release of acetylcholine in the rat brain in vivo. In time course studies, a
Publikováno v:
Journal of Neurochemistry. 57:1013-1018
Delta-sleep-inducing peptide (DSIP) stimulates the release of Met-enkephalin (Met-ENK) from superfused slices of the rodent lower brainstem in vitro. In our present study, DSIP (10(-10)-10(-9) M) induced a significant release of Met-ENK from medullar
Autor:
Bryan G. Johnson, Michael V. Johnston, Craig R. Salhoff, Darryle D. Schoepp, John W. McDonald
Publikováno v:
Journal of Neurochemistry. 56:1789-1796
This study explored further the function of the metabotropic excitatory amino acid receptor in the rat brain. The trans and cis isomers of (±)-1-amino-1,3-cyclopentane-dicarboxylic acid (ACPD) were characterized for relative affinities at ionotropic
Publikováno v:
Journal of Neurochemistry. 56:1394-1400
In the present study, the release of the neuropeptide cholecystokinin-8 (CCK) from purified nerve terminals (synaptosomes) of the rat hippocampus was characterized with respect to the subcellular distribution, the release upon addition of various age
Autor:
Joseph T. Coyle, James J. Vornov
Publikováno v:
Journal of Neurochemistry. 56:996-1006
In some animal models of ischemia, neuronal degeneration can be prevented by the selective antagonism of the N-methyl-D-aspartate (NMDA) glutamate receptor subtype, suggesting that glutamate released during ischemia causes injury by activating NMDA r
Publikováno v:
Journal of neurochemistry. 108(2)
In this study, we investigate the effects of chronic administration of (-)nicotine on the function of the NMDA-mediated modulation of [(3)H]dopamine (DA) release in rat prefrontal cortex (PFC) and nucleus accumbens (NAc). In the PFC synaptosomes NMDA
Autor:
Masatoshi Tanaka, Akinori Nishi, Helen S. Bateup, Mahomi Kuroiwa, Hideho Higashi, Takahide Shuto
Publikováno v:
Journal of Neurochemistry.
Dopamine D(1)-like receptors play a key role in dopaminergic signaling. In addition to G(s/olf)/adenylyl cyclase (AC)-coupled D(1) receptors, the presence of D(1)-like receptors coupled to G(q)/phospholipase C (PLC) has been proposed. Benzazepine D(1
Publikováno v:
Journal of neurochemistry. 106(4)
Although cannabinoid-induced behavioral sensitization and cross-sensitization with opiates has been recently demonstrated, no information is available on the associated state and responsiveness of dopamine (DA) transmission in the nucleus accumbens (