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pro vyhledávání: '"Martin Egli"'
Publikováno v:
Journal of Molecular Biology. 236:1154-1168
The water structure in three crystal forms of the left-handed Z-DNA hexamer [d(CGCGCG)]2 has been analyzed. Several common motifs have been found in the first hydration shells. On the convex surface, the major groove of the left-handed conformation,
Autor:
Alexander Rich, Gary J. Quigley, G. A. Van Der Marel, Christin A. Frederick, Loren Dean Williams, Martin Egli, Andrew H.-J. Wang, Giovanni Ughetto, J. H. Van Boom
Publikováno v:
Journal of molecular biology. 215(2)
The anthracyclines form an important family of cancer chemotherapeutic agents with a strong dependence of clinical properties on minor differences in chemical structure. We describe the X-ray crystallographic solution of the three-dimensional structu