Zobrazeno 1 - 10
of 11
pro vyhledávání: '"35"'
Autor:
Melissa Pineda, Kimberly R. Baxter, Bridget Szczypinski, Deborah M. Hinton, Eric S. Miller, Brian D. Gregory, Ann Hochschild
Publikováno v:
Journal of Molecular Biology. 344:1183-1197
Anti-sigma70 factors interact with sigma70 proteins, the specificity subunits of prokaryotic RNA polymerase. The bacteriophage T4 anti-sigma70 protein, AsiA, binds tightly to regions 4.1 and 4.2 of the sigma70 subunit of Escherichia coli RNA polymera
Autor:
Richard S. Hayward, Nobuyuki Fujita, Richard A. Malloch, Ashok Kumar, David A. Smillie, Akira Ishihama
Publikováno v:
Journal of molecular biology. 232(2)
It is known that Escherichia coli promoters having the major minus 10 consensus sequence TATAAT, but lacking significant resemblance to consensus in the minus 35 region, allow transcriptional initiation in vivo and in vitro if they have an additional
Publikováno v:
Journal of molecular biology. 206(4)
A mutation is described that alters the promoter specificity of σ70, the primary sigma factor of Escherichia coli RNA polymerase. In strains carrying both the mutant and wild-type sigma gene (rpoD), the mutant sigma causes a large increase in the ac
Autor:
Nigel L. Brown, Peter A. Lund
Publikováno v:
Journal of molecular biology. 205(2)
We report studies on deletion mutants of the regulatory region of the mercuric ion resistance ( mer ) genes of transposon Tn501, isolated from Pseudomonas aeruginosa . Transcription of the mer genes in Escherichia coli from the promoter P mer is regu
Autor:
Laura A. Johnson, Francis K. Insaidoo, Brian M. Baker, Daniel J. Powell, Tiffany K. Baxter, Oleg Y. Borbulevych, Nicholas P. Restifo
Publikováno v:
Journal of Molecular Biology. 372:1123-1136
Small structural changes in peptides presented by major histocompatibility complex (MHC) molecules often result in large changes in immunogenicity, supporting the notion that T cell receptors are exquisitely sensitive to antigen structure. Yet there
Publikováno v:
Journal of Molecular Biology. 240:119-126
A detailed kinetic analysis demonstrates that, in vitro , mutations in the P RM promoter of bacteriophage λ can increase the rate of open complex formation at the divergent, lytic promoter P R in either of two ways. (1) P - RM mutations, typified by
Publikováno v:
Journal of Molecular Biology. 229:26-36
To be aminoacylated by Escherichia coli methionyl-tRNA synthetase, a tRNA requires the presence of the methionine anticodon (CAU sequence). However, the importance in this reaction of the other nucleotides of tRNAs(Met) has still to be described. In
Autor:
Adnane Achour, Hans Grönlund, Marianne van Hage, Dan Hallén, Tanja Cirkovic Velickovic, Justus Adédoyin, Kurt D. Berndt, Daniel Badia-Martinez, Guro Gafvelin, Sarah Thunberg, L. Kaiser
Publikováno v:
Journal of Molecular Biology
Felis domesticus allergen 1(Fel d 1) is a 35 kDa tetrameric glycoprotein formed by two heterodimers which elicits IgE responses in 95% of patients with allergy to cat. We have previously established in vitro conditions for the appropriate folding of
Autor:
Mark L. Gonzalgo, Peter A. Jones, Jonathan D. Buckley, Allen S. Yang, Robert P. Millar, Jean-Marc Zingg
Publikováno v:
Journal of molecular biology. 258(2)
Cytosine to thymine transition mutations at the CpG dinucleotide are the most common point mutations in cancer and genetic disease. We calculated the in vivo rate of CpG mutation in the primate germline by deriving a primordial consensus sequence for
Publikováno v:
Journal of molecular biology. 223(4)
The formation of an intramolecular dG·dG·dC triplex in Escherichia coli cells is demonstrated at single-base resolution. The intramolecular dG·dG·dC triplex structure was probed in situ for E. coli cells containing plasmid DNAs with varying lengt