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Autor:
Leach Colin Andrew, Kenneth Wiggall, David R. Reavill, David J. Keeling, Shiona M. Laing, Thomas Henry Brown, Robert John Ife, Michael E. Parsons, Carolyn A. Price
Publikováno v:
Journal of medicinal chemistry. 33(2)
The 4-(arylamino)quinoline 4, previously described as an antiulcer compound, is shown to be an inhibitor of the gastric (H+/K+)-ATPase. It is postulated that 1-arylpyrrolo[3,2-c]quinolines 6 act as conformationally restrained analogues of 4. A series