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Autor:
Helsby NA; Auckland Cancer Society Research Centre, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand. n.helsby@auckland.ac.nz, Atwell GJ, Yang S, Palmer BD, Anderson RF, Pullen SM, Ferry DM, Hogg A, Wilson WR, Denny WA
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2004 Jun 03; Vol. 47 (12), pp. 3295-307.
Autor:
William R. Wilson, Robert F. Anderson, Dianne M. Ferry, Nuala A. Helsby, Alison Hogg, Shangjin Yang, Brian D. Palmer, Graham J. Atwell, William A. Denny, Susan M. Pullen
Publikováno v:
Journal of Medicinal Chemistry. 47:3295-3307
The 5-aziridinyl-2,4-dinitrobenzamide CB 1954 is a substrate for the oxygen-insensitive nitroreductase (NTR) from E. coli and is in clinical trial in combination with NTR-armed adenoviral vectors in a GDEPT protocol; CB 1954 is also of interest for s