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Autor:
Daniel Gonçalves Chaves, Marina Lobato Martins, Eduarda Bolina-Santos, Ricardo Andrade Carmo, Maria Clara Fernandes da Silva-Malta, Edel Figueiredo Barbosa-Stancioli
Publikováno v:
Journal of Medical Virology. 94:683-691
Prevalence of hepatitis C virus (HCV) is high in hemophilia A patients and the development of FVIII inhibitor is another challenge in the management of these individuals. The influence of HCV infection in the occurrence of inhibitors was investigated
Publikováno v:
Journal of Medical Virology. 93:6079-6088
Globally, 13% of all hepatitis C virus (HCV) infections are caused by genotype 4 (GT4), which consists of 17 subtypes with various levels of susceptibility to anti-HCV therapy. This genotype is endemic in the Middle East and Africa and has considerab
Autor:
Sheryl Gan, Wan Cheng Chow, Kian Sing Chan, Sobhana Thangaraju, Lynette Oon, Judith Chui Ching Wong, Marjorie Foo, Wee Ching Ng, Shi Min Woo, Kun Lee Lim, Kwai Peng Chan, Terence Yi Shern Kee, Rajneesh Kumar, Victoria Ekstrom
Publikováno v:
Journal of Medical Virology. 93:3738-3743
Early diagnosis remains key for effective prevention and treatment. Unfortunately, current screening with anti-hepatitis C virus antibody (anti-HCV Ab) test may have limited utility in the diagnosis of HCV infection and reinfection. This is of specia
Autor:
Bo Wu, Yu Ji, You Ge, Ling Su, Xiaoshan Li, Taha Hussein Musa, Yan He, Qian Ni, Guoping Du, Wei Li
Publikováno v:
Journal of Medical Virology. 91:401-410
Comprehensive data on hepatitis C virus (HCV) genotypes distribution is critical for treatment regimen selection, vaccine design, and drug development. This study aimed to understand the dynamic distribution of HCV genotypes in Mainland China. Three
Autor:
Roya Kahyesh‐Esfandiary, Zohreh-Azita Sadigh, Farah Bokharaei-Salim, Tahereh Donyavi, Alireza Najafi, Atousa Fakhim, Mohammad-Navid Bastani, Maryam Esghaei
Publikováno v:
Journal of Medical Virology. 91:107-114
Beta (β) thalassemia major is a genetic blood disorder with a deficiency in the hemoglobin beta chain, requiring blood transfusion therapy. Multiple blood transfusions increase the risk of transmitting blood-borne infections. The aim of this study i
Autor:
Ibrahim Amer, Shimaa El Sharawy, Ferial El-Kalla, Amany A. Ghazy, Hassan El Batae, Abdelrahman Kobtan, Shimaa M. Saied
Publikováno v:
Journal of Medical Virology. 90:1745-1749
BACKGROUND Hepatitis C virus (HCV) constitutes a global public health problem in Egypt, as it has the highest worldwide prevalence. This study aimed at determining the seroprevalence of HCV among the newcomer students of Kafrelsheikh University, Egyp
Autor:
Benjamin Emmanuel, Shyamasundaran Kottilil, Bhawna Poonia, Poonam Mathur, Xiaozhen Zhang, Michael C. Sneller
Publikováno v:
Journal of Medical Virology. 90:936-941
Mixed cryoglobulinemic vasculitis is associated with monoclonal B cell expansion in patients with chronic hepatitis C (HCV) infection. B cell depletion therapy using rituximab, a CD20 monoclonal antibody, has been successful in achieving remission fr
Publikováno v:
Journal of Medical Virology. 89:2165-2172
Aims: In virus-infected cells, pattern recognition receptors (PRRs) recruits their specific adaptor molecules, mitochondrial antiviral signaling protein (MAVS), TIR-domain-containing adapter-inducing interferon-β (TRIF) and TNF receptor associated f
Autor:
Amr M. El-deeb, Dina M. Rasheed Bahgat, Marwa Hassan, Rania H. Khalifa, Dalia A. Labib, Mohamed A. Kamel, Rasha Mohamad Hosny Shahin, Engy El Khateeb, Nermine Magdi Riad
Publikováno v:
Journal of Medical Virology. 89:1584-1589
At least 1 in 10 of the Egyptian population aged 15-59 is burdened with hepatitis C virus (HCV) infection, stamping Egypt the highest country harboring HCV worldwide. Considerable evidence supported the involvement of host genetic factors in the path
Publikováno v:
Journal of Medical Virology. 89:1048-1054
Objective Hepatitis C virus (HCV) genotypes 1b and 2a are the major cause of liver disease in northern China; however, conventional detection tools are labor-consuming, technically demanding, and costly. Here, we assessed the specificity, sensitivity