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Autor:
Changning Li, Puja Panwar Hazari, Abhishek Kumar, Supriya D. Mahajan, Ravikumar Aalinkeel, Anu Sharma, Mark T. Swihart, Rakesh Kumar Sharma
Publikováno v:
Journal of Materials Chemistry B. 9:2505-2514
Cannabidiol (CBD) has been shown to slow cancer cell growth and is toxic to human glioblastoma cell lines. Thus, CBD could be an effective therapeutic for glioblastoma. In the present study, we explored the anticancer effect of cannabidiol loaded mag
Publikováno v:
Journal of Materials Chemistry B. 9:1988-2000
Chemo/chemodynamic synergistic therapy is a promising strategy to improve the antitumor effect. However, hypoxia and a limited amount of hydrogen peroxide (H2O2) in the tumor microenvironment (TME) severely restrict the therapeutic efficacy of this c
Autor:
Yuanjiao Tang, Liyun Wang, Feng Yan, Jianbo Huang, Li Qiu, Chong Cheng, Lang Ma, Xi Xiang, Bihui Zhu
Publikováno v:
Journal of Materials Chemistry B. 7:4581-4591
Several kinds of therapeutic agents and methods are emerging to meet the increasing demand for a more effective rheumatoid arthritis (RA) therapy. However, developing an ultrasound (US)-responsive nanosystem for the treatment of RA is still filled wi
Publikováno v:
Journal of Materials Chemistry B. 7:1415-1426
The term synergism means that the overall therapeutic benefits should be greater than the sum of the effects of individual agents and that the optimal therapeutic efficacy can be achieved at reduced doses. Micellar systems usually fail to deliver mul
Autor:
Giacomo Biagiotti, Fabrizio Machetti, Maria Cristina Ligi, Helen Piwnica-Worms, Emily Powell, Erica Pranzini, Federica Pisaneschi, Stefano Cicchi, Giulia Tuci, David Piwnica-Worms, Seth T. Gammon, Paolo De Paoli, Giuliano Giambastiani
Publikováno v:
Journal of Materials Chemistry B 7 (2019): 2678–2687. doi:10.1039/c8tb03299h
info:cnr-pdr/source/autori:Biagiotti, Giacomo; Pisaneschi, Federica; Gammon, T. Seth; Machetti, Fabrizio; Ligi, Maria Cristina; Giambastiani, Giuliano; Tuci, Giulia; Powell, Emily; Piwnica-Worms, Helen; Pranzini, Erica; Paoli, Paolo; Cicchi, Stefano; Piwnica-Worms, David/titolo:Multiwalled carbon nanotubes for combination therapy: A biodistribution and efficacy pilot study/doi:10.1039%2Fc8tb03299h/rivista:Journal of Materials Chemistry B/anno:2019/pagina_da:2678/pagina_a:2687/intervallo_pagine:2678–2687/volume:7
info:cnr-pdr/source/autori:Biagiotti, Giacomo; Pisaneschi, Federica; Gammon, T. Seth; Machetti, Fabrizio; Ligi, Maria Cristina; Giambastiani, Giuliano; Tuci, Giulia; Powell, Emily; Piwnica-Worms, Helen; Pranzini, Erica; Paoli, Paolo; Cicchi, Stefano; Piwnica-Worms, David/titolo:Multiwalled carbon nanotubes for combination therapy: A biodistribution and efficacy pilot study/doi:10.1039%2Fc8tb03299h/rivista:Journal of Materials Chemistry B/anno:2019/pagina_da:2678/pagina_a:2687/intervallo_pagine:2678–2687/volume:7
A drug delivery system (DDS) for combined therapy, based on a short oxidized multiwalled carbon nanotube, is reported. It was prepared by exploiting a synthetic approach which allowed loading of two drugs, doxorubicin and metformin, the targeting age
Autor:
Xinyu Zhang, Fu Shi, Jun Huang, Jun Wu, Yang Kang, Junfu Zhang, Kunyong Ou, Binyuan Yan, Jun Pang, Dandan Li, Jia-Yuan Zhang
Publikováno v:
Journal of Materials Chemistry B. 7:251-264
For the treatment of malignant tumors, drug nanocarriers with long blood circulation time and ability to target the tumor microenvironment are promising therapeutic abilities. In this work, to systematically investigate the roles and functions of pol
Autor:
Woong Roeck Won, Kyung Taek Oh, Taehoon Sim, Jae Chang Kim, Eun Seong Lee, Chaemin Lim, Junseong Moon, Yuseon Shin, Yu Seok Youn
Publikováno v:
Journal of Materials Chemistry B. 7:4299-4308
Currently, one of the most important challenges in the development of nanotechnology-based anticancer treatments is the failure of nanoparticles to escape from the endo-lysosomal compartment and the resulting elimination of endocytosed nanoparticles
Publikováno v:
Journal of Materials Chemistry B. 6:5243-5247
Doxorubicin, one of the most effective antitumor drugs, causes serious adverse cardiac effects. As a derivative of tanshinone IIA, sodium tanshinone IIA sulfonate was exploited for curing cardiovascular disorders. The synergistic effect of the above
Autor:
Zhili Yu, Ergang Liu, Sunhui Chen, Jianxin Wang, Huining He, Meong-Cheol Shin, Qiuling Liang, Junxiao Ye, Lu Sun
Publikováno v:
Journal of Materials Chemistry B. 5:4060-4072
Coating supermagnetic iron oxide nanoparticles (SPIOs) with albumin would not only improve their in vivo stability but also improve their drug loading capacity, but current methods are either inefficient or time consuming. Herein, a single step synth
Publikováno v:
Journal of Materials Chemistry B. 5:3531-3540
Co-delivery of two or more chemotherapeutic agents via nanocarriers can provide an effective approach to maximize synergistic or additive effects. In this work, we developed novel nanodiamond (ND) based nanoparticle co-loading of doxorubicin (DOX) an