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Autor:
Xugang Dang, Feng Xu, Guoliang Li, Jingwen Xu, Xin Ge, Yan Yang, Mingzhen Zhang, Xiangji Yan, Yan-Ling Luo
Publikováno v:
Journal of Materials Chemistry B. 9:1297-1314
The efficacy of ongoing anticancer treatment is often compromised by some barriers, such as low drug content, nonspecific release of drug delivery system, and multidrug resistance (MDR) effect of tumors. Herein, in the research a novel functionalized
Autor:
Congrui Li, Dennis Huang, Yanmei He, Jun Cao, Zhengzhong Wu, Yutong Zhu, Shensheng Cai, Xuequan Zhang, Bin He, Ting Su
Publikováno v:
Journal of Materials Chemistry B. 8:5109-5116
Premature leakage of drugs during blood circulation and slow drug release at the tumor site are two major challenges that nanocarriers have to overcome to achieve successful cancer therapy. Herein, a dual core-crosslinked, redox-sensitive polymeric n
Autor:
Yuanjiao Tang, Liyun Wang, Feng Yan, Jianbo Huang, Li Qiu, Chong Cheng, Lang Ma, Xi Xiang, Bihui Zhu
Publikováno v:
Journal of Materials Chemistry B. 7:4581-4591
Several kinds of therapeutic agents and methods are emerging to meet the increasing demand for a more effective rheumatoid arthritis (RA) therapy. However, developing an ultrasound (US)-responsive nanosystem for the treatment of RA is still filled wi
Publikováno v:
Journal of Materials Chemistry B. 5:3531-3540
Co-delivery of two or more chemotherapeutic agents via nanocarriers can provide an effective approach to maximize synergistic or additive effects. In this work, we developed novel nanodiamond (ND) based nanoparticle co-loading of doxorubicin (DOX) an
Publikováno v:
Journal of Materials Chemistry B. 5:1542-1550
The development of cost-effective targeted drug delivery systems for cancer chemotherapy still remains a great challenging task. Here, we describe the synthesis and characterization of multifunctional polyethylenimine (PEI) as an effective vehicle to
Autor:
Ying Tian, Yunlei Zhang, Zhaogang Teng, Guangming Lu, Jian Xu, Jun Wen, Li Liu, Qi Zhang, Wei Tian, Lihui Yuwen, Tianpeng Shao, Yunyan Su, Yingwen Zhou
Publikováno v:
Journal of Materials Chemistry B. 4:7708-7717
Two-dimensional (2D) MoS2 nanosheets have attracted increasing attention in recent years owing to their various fascinating properties, particularly excellent near-infrared (NIR) photothermal feature. In this study, we synthesized a novel NIR-light-t
Publikováno v:
Journal of Materials Chemistry B. 4:360-370
Due to the high cost and uncertain success of new drug development, tremendous effort is devoted to increasing the efficacy of established anti-cancer drugs. Development of polymer prodrug conjugates has evolved recently in the nano-medicine field fo
Autor:
Song Luo, Ying Liu, Ying Tian, Shouju Wang, Yuanwei Pan, Huaijiang Yan, Guangming Lu, Leyong Zeng, Yanjun Li, Jiang Wu, Zhaogang Teng
Publikováno v:
Journal of Materials Chemistry B. 3:4330-4337
Multifunctional gold nanostructures effective at photothermal therapy (PTT) and high-quality X-ray/computed tomography (CT) imaging have drawn much attention in recent research. In particular, the development of improved PTT against cancer has been a
Publikováno v:
Journal of Materials Chemistry B. 3:7594-7603
Tumor-targeting, redox-responsive and high drug-loaded nanoparticles were synthesized from poly(ethylene glycol)-b-poly(l-lysine) (PEG-PLL) for enhanced cancer therapy. A hydrophobic drug camptothecin (CPT) was anchored to the lysine residual amines
Publikováno v:
Journal of Materials Chemistry B. 3:3297-3305
Ideal drug delivery systems should have prolonged circulation in blood, high accumulation in tumors with fast cellular uptake and burst drug release in cancer cells. Herein, a pH-sensitive small-molecule phospholipid prodrug based on phosphorylcholin