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Publikováno v:
Journal of Materials Chemistry B. 9:187-194
In this study, an enhanced anticancer strategy combining the chemotherapy from antineoplastics with the oxidative damage from a sulfur dioxide (SO2) prodrug is presented. Based on the characteristics of a high glutathione (GSH) level in the tumor mic
Publikováno v:
Journal of Materials Chemistry B. 8:216-225
Microneedle (MN) arrays offer an alternative approach to hypodermic injection via syringe needles. In this work, polyvinylpyrrolidone (PVP)-based fast dissolving MN arrays were developed in which the needle tips were loaded with chitosan nanoparticle
Publikováno v:
Journal of Materials Chemistry B. 8:534-545
Photodynamic therapy (PDT) is strongly O2 dependent. Therefore, its therapeutic effects are seriously hindered in hypoxic tumors. Red blood cells are responsible for delivering O2 in the blood. In this manuscript, biomimetic red blood cells (BRBCs) w
Autor:
Shiqi Yin, Lang Ma, Chao He, Ye Yang, Jiarui Yin, Weifeng Zhao, Xizheng Wu, Changsheng Zhao, Chong Cheng, Jue Zhang
Publikováno v:
Journal of Materials Chemistry B. 8:1960-1970
Recently emerged hemoperfusion absorbents, e.g. ion-exchange resin, activated carbon, and other porous materials, provide numerous novel possibilities to cure chronic liver failure (CLF) and renal failure (CRF). However, the limited adsorption perfor
Autor:
Jin-Ho Choy, Goeun Choi, Hanna Lee, Chun Gwon Park, Na Kyeong Lee, Young Bin Choy, Myung Hun Kim, Se Na Kim
Publikováno v:
Journal of Materials Chemistry B. 8:7914-7920
Brimonidine (BMD) is often prescribed as an eye drop to reduce the intraocular pressure (IOP) for glaucoma treatment. However, eye drops are limited by rapid clearance from the preocular surface, and hence a low ocular drug bioavailability. Therefore
Publikováno v:
Journal of Materials Chemistry B. 8:1739-1747
Gold nanoclusters (AuNCs) with an ultra-small size, as new inorganic photosensitizers, have been shown to be promising in photodynamic therapy (PDT), but their application has been restricted due to short blood circulation. It is therefore important
Publikováno v:
Journal of Materials Chemistry B. 7:460-468
The combination of chemotherapy and photodynamic therapy (PDT) using polymeric nanocarriers is effective for improving therapeutic efficiency against cancer. Yet, in most reported cases, due to the lack of synergistic mechanisms, chemotherapy and PDT
Autor:
Jeongmin Lee, Baskaran Purushothaman, Sol-Ji Park, Jin-Hyeok Choi, Sera Hong, Joon Myong Song, Annie Agnes Suganya Samson
Publikováno v:
Journal of Materials Chemistry B. 7:65-79
The combination of chemotherapy and photodynamic therapy (chemo-PDT) has been suggested as an alternative therapy for drug-resistant cancers. In this study, biotin-conjugated PEGylated photosensitizer (PS) self-assembled nanoparticles (meso-tetraphen
Autor:
Hannes Russmayer, Simone Weinberger, Claudia Tallian, Matthias G. Steiger, Lukas Skopek, Robert Vielnascher, Georg M. Guebitz, Vanessa Rumpler, Sara Vecchiato, Alessandro Pellis
Publikováno v:
Journal of Materials Chemistry B
Side streams from modern lignocellulose biorefineries have found value-added applications in various industries ranging from food to medical. Here, bioproduction of glutathione from glucose recovered from man-made cellulose fiber production was inves
Publikováno v:
Journal of Materials Chemistry B. 6:656-665
Recently, antibody-drug conjugates (ADC) have shown potential for cancer immunotherapy by tumor-targeted delivery of anticancer drugs. However, the development of ADC is subject to many restrictions, such as the payloads, stabilities and intracellula