Zobrazeno 1 - 10
of 18
pro vyhledávání: '"59"'
Autor:
Timo D. Müller, Stephan Sachs, Sebastian Cucuruz, Susanna M. Hofmann, Anna Götz, Yuanqing Gao, Samuel D. Wright, Maarit Lehti, Matthias H. Tschöp, Elizabeth Donelan, Stephen C. Woods, Chun-Xia Yi, Cynthia Striese
Publikováno v:
J. Lipid Res. 59, 1649-1659 (2018)
Journal of Lipid Research, Vol 59, Iss 9, Pp 1649-1659 (2018)
Journal of lipid research, 59(9), 1649-1659. American Society for Biochemistry and Molecular Biology Inc.
Journal of Lipid Research, Vol 59, Iss 9, Pp 1649-1659 (2018)
Journal of lipid research, 59(9), 1649-1659. American Society for Biochemistry and Molecular Biology Inc.
Meta-inflammation of hypothalamic areas governing energy homeostasis has recently emerged as a process of potential pathophysiological relevance for the development of obesity and its metabolic sequelae. The current model suggests that diet-induced n
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2277-2286 (2018)
Over the past two decades, intramuscular lipids have been viewed as a cause of insulin resistance due to their ability to suppress insulin-stimulated glucose uptake in skeletal muscle. Zinc-α2-glycoprotein (ZAG) is an adipokine involved in lipolysis
Autor:
Irina A. Pikuleva, Nicole El-Darzi, Ahab Alnemri, Tung Dao, Ying Song, Alexey M. Petrov, Natalia Mast, Joshua L. Dunaief, Aicha Saadane
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2368-2382 (2018)
Apolipoprotein E (APOE) is a component of lipid-transporting particles and a recognition ligand for receptors, which bind these particles. The APOE isoform ε2 is a risk factor for age-related macular degeneration; nevertheless, APOE absence in human
Autor:
Youjia Cao, Ying Liu, Yajun Duan, Ye Zhang, Yuanli Chen, Miao Yu, Xiaoju Li, Xiaoxiao Yang, Jian Liu, Jihong Han, Zhuo Wei, Xingzhe Ma, Chuanrui Ma
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2287-2296 (2018)
Production of 25-hydroxycholesterol (25HC), a potent inhibitor of viral infection, is catalyzed by cholesterol 25-hydroxylase (CH25H). We previously reported that 25HC induced CH25H expression in a liver X receptor (LXR)-dependent manner, implying th
NPC1L1-dependent intestinal cholesterol absorption requires ganglioside GM3 in membrane microdomains
Autor:
Yuta Odagiri, Yui Kikuchi, Wataru Nihei, Yumi Tamura, Hirotaka Hayamizu, Masakazu Nagafuku, Jin-ichi Inokuchi, Kazuya Kabayama, Hirotaka Kanoh, Kenta Arai, Kei-ichiro Inamori, Koichi Fukase, Lucas Veillon
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2181-2187 (2018)
Intestinal cholesterol absorption is a key regulator of systemic cholesterol homeostasis. Excessive dietary cholesterol and its intestinal uptake lead to hypercholesterolemia, a major risk factor for cardiovascular disease. Intestinal cholesterol upt
Autor:
Guolin Li, Kristopher W. Krausz, Chad Brocker, Jiang Yue, Frank J. Gonzalez, Donghwan Kim, Tingting Yan, Thomas J. Velenosi, Daxesh P. Patel
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2140-2152 (2018)
PPARα (PPARA), expressed in most oxidative tissues, is a major regulator of lipid homeostasis; hepatic PPARA plays a critical role during the adaptive fasting response by promoting FA oxidation (FAO). To clarify whether extrahepatic PPARA activity c
Autor:
Samar M. Hammad, Marina Cuchel, Daniel J. Rader, Meghan T. Walsh, M. Mahmood Hussain, Jahangir Iqbal
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2084-2097 (2018)
Sphingolipids, including ceramide, SM, and hexosylceramide (HxCer), are carried in the plasma by lipoproteins. They are possible markers of metabolic diseases, but little is known about their control. We previously showed that microsomal triglyceride
Autor:
Jens, Madsen, Madhuriben H, Panchal, Rose-Marie A, Mackay, Mercedes, Echaide, Grielof, Koster, Giancarlo, Aquino, Nicola, Pelizzi, Jesus, Perez-Gil, Fabrizio, Salomone, Howard W, Clark, Anthony D, Postle
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1880-1892 (2018)
Journal of Lipid Research
Journal of Lipid Research
Secreted pulmonary surfactant phosphatidylcholine (PC) has a complex intra-alveolar metabolism that involves uptake and recycling by alveolar type II epithelial cells, catabolism by alveolar macrophages, and loss up the bronchial tree. We compared th
Autor:
Shinobu Miyazaki-Anzai, Audrey L. Keenan, Shohei Kohno, Masashi Masuda, Moshe Levi, Makoto Miyazaki, Yuji Shiozaki
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1709-1713 (2018)
Simultaneous activation of bile acid receptors farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5) by INT-767 significantly reduces atherosclerotic formation. In this study, we investigated the effect of simultaneous inactiva
Autor:
Marisa R. Morrow, Brian G. Sutherland, Jane Y. Edwards, Dawn E. Telford, Amy C. Burke, Maria Drangova, Cynthia G. Sawyez, Murray W. Huff
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1714-1728 (2018)
Medical Biophysics Publications
Bone and Joint Institute
Medical Biophysics Publications
Bone and Joint Institute
Copyright © 2018 Burke et al. Obesity and its associated metabolic dysfunction and cardiovascular disease risk represent a leading cause of adult morbidity worldwide. Currently available pharmacological therapies for obesity have had limited success