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Autor:
Adam Taleb, Peter Willeit, Shahzada Amir, Thomas Perkmann, Maria Ozsvar Kozma, Martin L. Watzenböck, Christoph J. Binder, Joseph L. Witztum, Sotirios Tsimikas
Publikováno v:
Journal of lipid research, vol 64, iss 6
Immunoglobulin M (IgM) autoantibodies to oxidation-specific epitopes (OSEs) can be present at birth and protect against atherosclerosis in experimental models. This study sought to determine whether high titers of IgM titers to OSE (IgM OSE) are asso
Publikováno v:
Journal of lipid research. 63(11)
Human parturition is associated with massive arachidonic acid (AA) mobilization in the amnion, indicating that large amounts of AA-derived eicosanoids are required for parturition. Prostaglandin E2 (PGE2) synthesized from the cyclooxygenase (COX) pat
Publikováno v:
Journal of lipid research. 63(12)
Lipids perform multiple biological functions and reflect the physiology and pathology of cells, tissues, and organs. Here, we sought to understand lipid content in relation to tumor pathology by characterizing phospholipids and sphingolipids in the o
Autor:
Jenny Voggel, Gregor Fink, Magdalena Zelck, Maria Wohlfarth, Julia M. Post, Laura Bindila, Manfred Rauh, Kerstin Amann, Miguel A. Alejandre Alcázar, Jörg Dötsch, Kai-Dietrich Nüsken, Eva Nüsken
Publikováno v:
Journal of lipid research. 63(11)
Intrauterine growth restriction (IUGR) predisposes to chronic kidney disease via activation of proinflammatory pathways, and omega-3 PUFAs (n-3 PUFAs) have anti-inflammatory properties. In female rats, we investigated 1) how an elevated dietary n-3/n
Autor:
Simona Zarini, Joseph T. Brozinick, Karin A. Zemski Berry, Amanda Garfield, Leigh Perreault, Anna Kerege, Hai Hoang Bui, Phil Sanders, Parker Siddall, Ming Shang Kuo, Bryan C. Bergman
Publikováno v:
Journal of lipid research. 63(10)
Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spann
Autor:
Garret A. FitzGerald
Publikováno v:
Journal of lipid research. 63(7)
Autor:
Lelieveld, Lindsey T, Gerhardt, Sophie, Maas, Saskia, Zwiers, Kimberley C, de Wit, Claire, Beijk, Ernst H, Ferraz, Maria J, Artola, Marta, Meijer, Annemarie H, Tudorache, Christian, Salvatori, Daniela, Boot, Rolf G, Aerts, Johannes M F G, Anatomie en fysiologie, CS_Locomotion, CS_Cancer
Publikováno v:
Journal of lipid research, 64(5):100199. American Society for Biochemistry and Molecular Biology Inc.
Journal of Lipid Research, 63(5), 1. American Society for Biochemistry and Molecular Biology Inc.
Lelieveld, L T, Gerhardt, S, Maas, S, Zwiers, K C, de Wit, C, Beijk, E H, Ferraz, M J, Artola, M, Meijer, A H, Tudorache, C, Salvatori, D, Boot, R G & Aerts, J M F G 2022, ' Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish ', Journal of Lipid Research, vol. 64, no. 5, 100199 . https://doi.org/10.1016/j.jlr.2022.100199
Journal of Lipid Research, 63(5). Elsevier BV
Journal of Lipid Research, 64(5):100199. American Society for Biochemistry and Molecular Biology Inc.
Journal of Lipid Research, 63(5), 1. American Society for Biochemistry and Molecular Biology Inc.
Lelieveld, L T, Gerhardt, S, Maas, S, Zwiers, K C, de Wit, C, Beijk, E H, Ferraz, M J, Artola, M, Meijer, A H, Tudorache, C, Salvatori, D, Boot, R G & Aerts, J M F G 2022, ' Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish ', Journal of Lipid Research, vol. 64, no. 5, 100199 . https://doi.org/10.1016/j.jlr.2022.100199
Journal of Lipid Research, 63(5). Elsevier BV
Journal of Lipid Research, 64(5):100199. American Society for Biochemistry and Molecular Biology Inc.
In Gaucher disease (GD), the deficiency of glucocerebrosidase causes lysosomal accumulation of glucosylceramide (GlcCer), which is partly converted by acid ceramidase to glucosylsphingosine (GlcSph) in the lysosome. Chronically elevated blood and tis
Publikováno v:
Journal of lipid research. 63(11)
The small intestinal epithelium has classically been envisioned as a conduit for nutrient absorption, but appreciation is growing for a larger and more dynamic role for enterocytes in lipid metabolism. Considerable gaps remain in our knowledge of thi
Autor:
Hajime Takei, Seiko Narushima, Mitsuyoshi Suzuki, Genta Kakiyama, Takahiro Sasaki, Tsuyoshi Murai, Yuichiro Yamashiro, Hiroshi Nittono
Publikováno v:
Journal of lipid research. 63(10)
Although most bile acids (BAs) in feces are present in noncovalent forms that can be extracted with ethanol, non-negligible amounts of saponifiable BAs are also present. It is a major concern that such saponifiable BAs are routinely omitted from feca
Autor:
Eric J. Lawitz, Kelvin W. Li, Edna Nyangau, Tyler John Field, Jen-Chieh Chuang, Andrew Billin, Lulu Wang, Ya Wang, Ryan S. Huss, Chuhan Chung, G. Mani Subramanian, Robert P. Myers, Marc K. Hellerstein
Publikováno v:
Journal of lipid research, vol 63, iss 9
De novo lipogenesis (DNL) converts carbon substrates to lipids. Increased hepatic DNL could contribute to pathogenic liver triglyceride accumulation in nonalcoholic steatohepatitis (NASH) and therefore may be a potential target for pharmacological in