Zobrazeno 1 - 10
of 12
pro vyhledávání: '"59"'
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 391-399 (2018)
Journal of lipid research, vol 59, iss 2
Journal of lipid research, vol 59, iss 2
Elevated plasma LDL cholesterol is the dominant risk factor for the development of atherosclerosis and cardiovascular disease. Deficiency in the LDL receptor (LDLR) is a major cause of familial hypercholesterolemia in humans, and the LDLR knockout mo
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2349-2359 (2018)
Dietary fat absorption takes place in the intestine, and the liver mobilizes endogenous fat to other tissues by synthesizing lipoproteins that require apoB and microsomal triglyceride transfer protein (MTP). Dietary fat triggers the synthesis of oleo
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 7, Pp 1114-1131 (2018)
Cholesterol is required for maintenance of plasma membrane fluidity and integrity and for many cellular functions. Cellular cholesterol can be obtained from lipoproteins in a selective pathway of HDL-cholesteryl ester (CE) uptake without parallel apo
Autor:
Alaa Sirwi, M. Mahmood Hussain
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 7, Pp 1094-1102 (2018)
A better understanding of intracellular lipoprotein assembly may help identify proteins with important roles in lipid disorders. apoB-containing lipoproteins (B-lps) are macromolecular lipid and protein micelles that act as specialized transport vehi
Autor:
W. Timothy Garvey, Complications Trial, Jamie R. Wood, Petar Alaupovic, Arpita Basu, Timothy J. Lyons, David S. Schade, Julie A. Stoner, Ying Zhang, Richard L. Klein, Alicia J. Jenkins, Diabetes Control, Maria F. Lopes-Virella
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 872-883 (2018)
Circulating apolipoprotein-defined lipoprotein subclasses (ADLS) and apolipoproteins predict vascular events in the general and type 2 diabetes populations, but data in T1D are limited. We examined associations of ADLS, serum apolipoproteins, and con
Autor:
Daniel J. Rader, Naqi Haider, Venkata R M Chavali, Michael C. Phillips, Nicholas N. Lyssenko, Wanzhen Jiao, Antonino Picataggi, Eleonora Cipollari
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1927-1939 (2018)
Cholesterol-containing soft drusen and subretinal drusenoid deposits (SDDs) occur at the basolateral and apical side of the retinal pigment epithelium (RPE), respectively, in the chorioretina and are independent risk factors for late age-related macu
Autor:
Patrick Couture, Jean-Philippe Drouin-Chartier, Jean-Charles Hogue, Benoît Lamarche, Valéry Lemelin, André J. Tremblay
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1501-1509 (2018)
Intestinal triglyceride (TG)-rich lipoproteins (TRLs) are important in the pathogenesis of atherosclerosis in insulin resistance (IR). We investigated the association of plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) concentrations with
Autor:
Stephen J. Demosky, G D Talley, Jeffrey M. Hoeg, Silvia Santamarina-Fojo, Boris L. Vaisman, Jian Wang, H. Bryan Brewer, Margaret E. Brousseau
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 8, Pp 1558-1567 (1998)
Familial hypercholesterolemia (FH), a disease caused by a variety of mutations in the low density lipopro- tein receptor (LDLr) gene, leads not only to elevated LDL- cholesterol (C) concentrations but to reduced high density lipoprotein (HDL)-C and a
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 11, Pp 2372-2382 (1996)
Guinea pigs were fed 15% (w/W) fat, high in lauric and myristic acids, a diet known to produce hypercholesterolemia in these animals. The diet was given alone or in combination with four doses of atorvastatin equivalent to 1, 3, 10, and 20 mg/kg per
Autor:
John S. Parks, Abraham K. Gebre
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 2, Pp 305-315 (1991)
To determine the effect of isocaloric substitution of dietary fish oil for lard on the physical and chemical properties of plasma low density lipoproteins (LDL), ten adult male cynomolgus monkeys were fed diets containing 11% (by weight) fish oil or