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pro vyhledávání: ''
Autor:
Anne Laure Rerole, Alain Carrié, Samir Saheb, David Masson, Wilfried Le Goff, Isabelle Fournel, Randa Bittar, Hélène Choubley, Thomas Gautier, Jean-Pierre Quenot, Jean-Paul Pais de Barros, Auguste Dargent, Laurent Lagrost
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1776-1783 (2020)
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
International audience; Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient to improve outcome during septic shock. An extracorporeal removal
Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort
Autor:
Tiziano Lucchi, Tiziana Sampietro, Giuliano Boscutti, Fabrizio Veglia, Alice Ossoli, Loreto Gesualdo, Marcello Arca, Laura Calabresi, Laura D'Erasmo, Chiara Pavanello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1784-1788 (2020)
J Lipid Res
J Lipid Res
Familial LCAT deficiency (FLD) is a rare genetic disorder of HDL metabolism, caused by loss-of-function mutations in the LCAT gene and characterized by a variety of symptoms including corneal opacities and kidney failure. Renal disease represents the
Autor:
Ryszard Podemski, Małgorzata Bilińska, Robert K. Yu, Ewa Jaskiewicz, Wojciech Fortuna, Zdzislaw M. Szulc, Maria Podbielska, Toshio Ariga, Anna Pokryszko-Dragan, Ewa Kurowska, Edward L. Hogan
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1464-1479 (2020)
Journal of Lipid Research
Journal of Lipid Research
Multiple sclerosis (MS) is a CNS disease characterized by immune-mediated demyelination and progressive axonal loss. MS-related CNS damage and its clinical course have two main phases: active and inactive/progressive. Reliable biomarkers are being so
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1504-1511 (2020)
J Lipid Res
J Lipid Res
Accompanied with nutrition transition, non-HDL-C levels of individuals in Asian countries has increased rapidly, which has caused the global epicenter of nonoptimal cholesterol to shift from Western countries to Asian countries. Thus, it is critical
Autor:
Hideaki Bujo, Akihito Takei, Hisataka Yamazaki, Jun-ichi Osuga, Shoko Takei, Manabu Takahashi, Masayuki Kuroda, Adriaan G. Holleboom, Shuichi Nagashima, Tetsuji Wakabayashi, Shun Ishibashi, Daisuke Yamamuro, Kenta Okada
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 9, Pp 1287-1299 (2020)
J Lipid Res
Journal of lipid research, 61(9), 1287-1299. American Society for Biochemistry and Molecular Biology Inc.
J Lipid Res
Journal of lipid research, 61(9), 1287-1299. American Society for Biochemistry and Molecular Biology Inc.
The acyltransferase LCAT mediates FA esterification of plasma cholesterol. In vitro studies have shown that LCAT also FA-esterifies several oxysterols, but in vivo evidence is lacking. Here, we measured both free and FA-esterified forms of sterols in
Autor:
Ying Gao, Raul D. Santos, Qi Hua, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Hui-Wen Zhang, Ye-Xuan Cao, Yan-Fang Li, Yan Zhang, Rui-Xia Xu, Jian-Jun Li, Jing-Lu Jin, Hui-Hui Liu
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 9, Pp 1254-1262 (2020)
J Lipid Res
J Lipid Res
TG-rich lipoprotein (TRL)-related biomarkers, including TRL-cholesterol (TRL-C), remnant-like lipoprotein particle-cholesterol (RLP-C), and apoC-III have been associated with atherosclerosis. However, their prognostic values have not been fully deter
Autor:
Peter J. Meikle, Patrice Thérond, Alexina Orsoni, Ricardo Tan, Philippe Giral, Paul Robillard, Anh Nguyen, M. John Chapman, Natalie A. Mellett
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (6), pp.911-932. ⟨10.1194/jlr.P119000543⟩
Journal of Lipid Research, Vol 61, Iss 6, Pp 911-932 (2020)
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (6), pp.911-932. ⟨10.1194/jlr.P119000543⟩
Journal of Lipid Research, Vol 61, Iss 6, Pp 911-932 (2020)
J Lipid Res
International audience; Atherogenic LDL particles are physicochemically and metabolically heterogeneous. Can bioactive lipid cargo differentiate LDLsubclasses, and thus potential atherogenicity? What is the effect of statin treatment? Obese hypertrig
Autor:
Salman Azhar, Wei Wang, Wen-Jun Shen, Qui Shuo, Yiqiang Zhang, Xiaoming Hou, Kathrin B. Hasbargen, Fredric B. Kraemer, David A. Bernlohr
Publikováno v:
J Lipid Res
Adipocytes take up long chain FAs through diffusion and protein-mediated transport, whereas FA efflux is considered to occur by diffusion. To identify potential membrane proteins that are involved in regulating FA flux in adipocytes, the expression l
Autor:
Phillip E. Melton, Natalie A. Mellett, Peter J. Meikle, Gerald F. Watts, Nina S. McCarthy, Gemma Cadby, Marie-Pierre Dubé, Eric K. Moses, Joseph Hung, Kevin Huynh, John Beilby, Corey Giles, John Blangero
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 4, Pp 537-545 (2020)
J Lipid Res
J Lipid Res
CVD is the leading cause of death worldwide, and genetic investigations into the human lipidome may provide insight into CVD risk. The aim of this study was to estimate the heritability of circulating lipid species and their genetic correlation with
Autor:
John P. Kane, Grace Marie Jones, Alejandro Gugliucci, Kathleen Mulligan, Russell Caccavello, Clive R. Pullinger, Jean-Marc Schwarz, Sergiu P. Palii
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 3, Pp 455-463 (2020)
Journal of lipid research, vol 61, iss 3
J Lipid Res
Journal of lipid research, vol 61, iss 3
J Lipid Res
Elevated levels of triglyceride-rich lipoproteins (TRLs), both fasting and postprandial, are associated with increased risk for atherosclerosis. However, guidelines for treatment are defined solely by fasting lipid levels, even though postprandial li