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Autor:
Anne Laure Rerole, Alain Carrié, Samir Saheb, David Masson, Wilfried Le Goff, Isabelle Fournel, Randa Bittar, Hélène Choubley, Thomas Gautier, Jean-Pierre Quenot, Jean-Paul Pais de Barros, Auguste Dargent, Laurent Lagrost
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1776-1783 (2020)
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
International audience; Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient to improve outcome during septic shock. An extracorporeal removal
Autor:
Graeme I. Lancaster, Denis Sviridov, Nigora Mukhamedova, Takahiro Kameda, Gerard Pernes, Peter J. Meikle, Ryunosuke Ohkawa, Boris L. Vaisman, Andrew J. Murphy, Ayuko Hara, Ying Fu, Michael Ditiatkovski, Shao-Jui Lai, Paul J. Nestel, Alan T. Remaley, Hann Low, Dmitri Sviridov, Minoru Tozuka, Yuna Horiuchi, Mai Sasaoka, Azusa Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
J Lipid Res
J Lipid Res
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort
Autor:
Tiziano Lucchi, Tiziana Sampietro, Giuliano Boscutti, Fabrizio Veglia, Alice Ossoli, Loreto Gesualdo, Marcello Arca, Laura Calabresi, Laura D'Erasmo, Chiara Pavanello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1784-1788 (2020)
J Lipid Res
J Lipid Res
Familial LCAT deficiency (FLD) is a rare genetic disorder of HDL metabolism, caused by loss-of-function mutations in the LCAT gene and characterized by a variety of symptoms including corneal opacities and kidney failure. Renal disease represents the
Autor:
Floyd E. Dewhirst, Amanda Rahmlow, Michael B. Smith, Anthony A. Provatas, Robert B. Clark, Jeremy L. Balsbaugh, Frank C. Nichols, Mark W. Maciejewski
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1645-1657 (2020)
J Lipid Res
J Lipid Res
Porphyromonas gingivalis is a Gram-negative anaerobic periodontal microorganism strongly associated with tissue-destructive processes in human periodontitis. Following oral infection with P. gingivalis, the periodontal bone loss in mice is reported t
Publikováno v:
J Lipid Res
Journal of Lipid Research, Vol 61, Iss 12, Pp 1605-1616 (2020)
Journal of Lipid Research, Vol 61, Iss 12, Pp 1605-1616 (2020)
ABCB4/MDR3 is located in the canalicular membrane of hepatocytes and translocates PC-lipids from the cytoplasmic to the extracellular leaflet. ABCB4 is an ATP-dependent transporter that reduces the harsh detergent effect of the bile salts by countera
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1687-1696 (2020)
J Lipid Res
J Lipid Res
Lipoprotein (a) [Lp(a)] is characterized by an LDL-like composition in terms of lipids and apoB100, and by one copy of a unique glycoprotein, apo(a). The apo(a) structure is mainly based on the repetition of tandem kringle domains with high homology
Autor:
Ryszard Podemski, Małgorzata Bilińska, Robert K. Yu, Ewa Jaskiewicz, Wojciech Fortuna, Zdzislaw M. Szulc, Maria Podbielska, Toshio Ariga, Anna Pokryszko-Dragan, Ewa Kurowska, Edward L. Hogan
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1464-1479 (2020)
Journal of Lipid Research
Journal of Lipid Research
Multiple sclerosis (MS) is a CNS disease characterized by immune-mediated demyelination and progressive axonal loss. MS-related CNS damage and its clinical course have two main phases: active and inactive/progressive. Reliable biomarkers are being so
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1504-1511 (2020)
J Lipid Res
J Lipid Res
Accompanied with nutrition transition, non-HDL-C levels of individuals in Asian countries has increased rapidly, which has caused the global epicenter of nonoptimal cholesterol to shift from Western countries to Asian countries. Thus, it is critical
Autor:
Maureen A. Kane, Jace W. Jones, Thomas J. MacVittie, Hongbing Wang, Peter W. Swaan, Linhao Li, Stephanie J. Shiffka, Ann M. Farese
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1524-1535 (2020)
J Lipid Res
J Lipid Res
Bile acids (BAs) have been established as ubiquitous regulatory molecules implicated in a large variety of healthy and pathological processes. However, the scope of BA heterogeneity is often underrepresented in current literature. This is due in part
Autor:
Maren C. Podszun, Dennis D. Lin, Natalia Y. Kedishvili, Philip M. Brown, Olga V. Belyaeva, Wenchang Zhou, Yanling Ma, Yaron Rotman, Suman Karki
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1400-1409 (2020)
J Lipid Res
J Lipid Res
Human genetic studies recently identified an association of SNPs in the 17-β hydroxysteroid dehydrogenase 13 (HSD17B13) gene with alcoholic and nonalcoholic fatty liver disease development. Mutant HSD17B13 variants devoid of enzymatic function have