Zobrazeno 1 - 9
of 9
pro vyhledávání: ''
Autor:
Maria Laura Gennaro, Petros C. Karakousis, Valentina Guerrini, Hugh Salamon, Natalie Bruiners, Ken D. Yamaguchi, Noton K. Dutta
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
Journal of Lipid Research, Vol 61, Iss 12, Pp 1617-1628 (2020)
The rise of drug-resistant tuberculosis poses a major risk to public health. Statins, which inhibit both cholesterol biosynthesis and protein prenylation branches of the mevalonate pathway, increase anti-tubercular antibiotic efficacy in animal model
Autor:
Denise V. Kratschmar, Sharavan Kanagaratnam, Alex Odermatt, Anton M. Jetten, Silvia G. Inderbinen, Hideaki Yamaguchi, Katharina Beck
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 60, Iss 9, Pp 1535-1546 (2019)
Journal of Lipid Research, Vol 60, Iss 9, Pp 1535-1546 (2019)
Oxysterols previously were considered intermediates of bile acid and steroid hormone biosynthetic pathways. However, recent research has emphasized the roles of oxysterols in essential physiologic processes and in various diseases. Despite these disc
Autor:
Hella A. Bolck, Arnold von Eckardstein, Peter Schraml, Srividya Velagapudi, Mustafa Yalcinkaya, Lucia Rohrer, Holger Moch
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 59, Iss 11, Pp 2188-2201 (2018)
Journal of Lipid Research, Vol 59, Iss 11, Pp 2188-2201 (2018)
Clear-cell renal cell carcinomas (ccRCCs) are characterized by inactivation of the von Hippel-Lindau (VHL) gene and intracellular lipid accumulation by unknown pathomechanisms. The immunochemical analysis of 356 RCCs revealed high abundance of apoA-I
Autor:
Michael Doherty, Ana M. Valdes, Abhishek Abhishek, Petros Pousinis, Victoria Chapman, Massimo Mangino, Cristina Menni, Srinivasarao Ravipati, David A. Barrett
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 59, Iss 9, Pp 1763-1770 (2018)
Journal of Lipid Research, Vol 59, Iss 9, Pp 1763-1770 (2018)
Omega-6 fatty acids are important inflammatory mediators increased in joints with osteoarthritis (OA) joints. To investigate the relationship between omega-6 fatty acids and knee OA 22 omega-6 lipids (arachidonic acid, linoleic acid and 20 oxylipins)
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 59, Iss 6, Pp 1034-1045 (2018)
Journal of Lipid Research, Vol 59, Iss 6, Pp 1034-1045 (2018)
Acute respiratory distress syndrome (ARDS) is associated with a severe pro-inflammatory response; although decreased plasma cholesterol concentration has been linked to systemic inflammation, any association of phospholipid metabolic pathways with AR
Autor:
Boden H. Vanderloop, Minu Chaudhuri, Ujjal K. Singha, W. David Nes, Medhanie E. Kidane, Crista D. Thomas, Wenxu Zhou, Emilio Ramos
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 58, Iss 12, Pp 2310-2323 (2017)
Journal of Lipid Research, Vol 58, Iss 12, Pp 2310-2323 (2017)
Ergosterol biosynthesis pathways essential to pathogenic protozoa growth and absent from the human host offer new chokepoint targets. Here, we present characterization and cell-based interference of Acanthamoeba spp sterol 24-/28-methylases (SMTs) th
Autor:
Alfred Tau Liang Gan, Qiao Fan, Ian Yeo, Rajendra S. Apte, Tien Yin Wong, Chiea Chuen Khor, E. Shyong Tai, Ranjana Mathur, Miao Ling Chee, Ching-Yu Cheng, Chui Ming Gemmy Cheung
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 58, Iss 9, Pp 1785-1796 (2017)
Journal of Lipid Research, Vol 58, Iss 9, Pp 1785-1796 (2017)
Disturbance in lipid metabolism has been suggested as a major pathogenic factor for age-related macular degeneration (AMD). Conventional lipid measures have been inconsistently associated with AMD. Other factors that can alter lipid metabolism includ
Autor:
Genfu Tang, Xiangyi Kong, Min Zhao, Fan Fan Hou, Yanhong Liu, Yi Wang, Xianhui Qin, Xiping Xu, Fangfang Fan, Wen Wang, Binyan Wang, Yong Huo, Yupeng Wang, Yu Wang, Scott A. Venners, Ningling Sun, Wei Gao, Yan Zhang, Jianping Li, Shanqun Jiang
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 58, Iss 1, Pp 256-266 (2017)
Journal of Lipid Research, Vol 58, Iss 1, Pp 256-266 (2017)
The aim of the present study was to examine the association between peripheral differential leukocyte counts and dyslipidemia in a Chinese hypertensive population. A total of 10,866 patients with hypertension were enrolled for a comprehensive assessm
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 57, Iss 12, Pp 2225-2234 (2016)
Journal of Lipid Research, Vol 57, Iss 12, Pp 2225-2234 (2016)
Phosphatidylcholine (PC) species in human plasma are used as biomarkers of disease. PC biomarkers are often limited by the inability to separate isobaric PCs. In this work, we developed a targeted shotgun approach for analysis of isobaric and isomeri