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Autor:
Anne Laure Rerole, Alain Carrié, Samir Saheb, David Masson, Wilfried Le Goff, Isabelle Fournel, Randa Bittar, Hélène Choubley, Thomas Gautier, Jean-Pierre Quenot, Jean-Paul Pais de Barros, Auguste Dargent, Laurent Lagrost
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1776-1783 (2020)
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
Journal of Lipid Research
Journal of Lipid Research, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
J Lipid Res
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2020, 61 (12), pp.1776-1783. ⟨10.1194/jlr.RA120001132⟩
International audience; Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient to improve outcome during septic shock. An extracorporeal removal
Autor:
Graeme I. Lancaster, Denis Sviridov, Nigora Mukhamedova, Takahiro Kameda, Gerard Pernes, Peter J. Meikle, Ryunosuke Ohkawa, Boris L. Vaisman, Andrew J. Murphy, Ayuko Hara, Ying Fu, Michael Ditiatkovski, Shao-Jui Lai, Paul J. Nestel, Alan T. Remaley, Hann Low, Dmitri Sviridov, Minoru Tozuka, Yuna Horiuchi, Mai Sasaoka, Azusa Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1577-1588 (2020)
J Lipid Res
J Lipid Res
Lipoproteins play a key role in transport of cholesterol to and from tissues. Recent studies have also demonstrated that red blood cells (RBCs), which carry large quantities of free cholesterol in their membrane, play an important role in reverse cho
Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort
Autor:
Tiziano Lucchi, Tiziana Sampietro, Giuliano Boscutti, Fabrizio Veglia, Alice Ossoli, Loreto Gesualdo, Marcello Arca, Laura Calabresi, Laura D'Erasmo, Chiara Pavanello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1784-1788 (2020)
J Lipid Res
J Lipid Res
Familial LCAT deficiency (FLD) is a rare genetic disorder of HDL metabolism, caused by loss-of-function mutations in the LCAT gene and characterized by a variety of symptoms including corneal opacities and kidney failure. Renal disease represents the
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1504-1511 (2020)
J Lipid Res
J Lipid Res
Accompanied with nutrition transition, non-HDL-C levels of individuals in Asian countries has increased rapidly, which has caused the global epicenter of nonoptimal cholesterol to shift from Western countries to Asian countries. Thus, it is critical
Autor:
Adam G. Schwaid, Jessica Ward, Nicole L. Nedoma, Lise R. Hoth, Meihua Tu, Ravi G. Kurumbail, Seungil Han, Allan R. Reyes, Francis Rajamohan
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 8, Pp 1192-1202 (2020)
Journal of Lipid Research
Journal of Lipid Research
Lysosomal acid lipase (LAL) is a serine hydrolase that hydrolyzes cholesteryl ester (CE) and TGs delivered to the lysosomes into free cholesterol and fatty acids. LAL deficiency due to mutations in the LAL gene (LIPA) results in accumulation of TGs a
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 8, Pp 1221-1231 (2020)
J Lipid Res
J Lipid Res
The final step of the CDP-ethanolamine pathway is catalyzed by ethanolamine phosphotransferase 1 (EPT1) and choline/EPT1 (CEPT1). These enzymes are likely involved in the transfer of ethanolamine phosphate from CDP-ethanolamine to lipid acceptors suc
Autor:
Yan Liu, Richard E. Morton
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 8, Pp 1168-1179 (2020)
J Lipid Res
J Lipid Res
Cholesteryl ester transfer protein (CETP) facilitates the net transfer of cholesteryl esters (CEs) and TGs between lipoproteins, impacting the metabolic fate of these lipoproteins. Previous studies have shown that a CETP antibody can alter CETP's pre
Autor:
Naoko Sawada, Toshihiro Aiuchi, Yuji Hamazaki, Rina Kato, Masaki Kikuchi, Shinji Koba, Hiroyuki Itabe, Sanju Iwamoto, Takashi Takaki, Takashi Obama
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 6, Pp 816-829 (2020)
J Lipid Res
J Lipid Res
Oxidized LDL (oxLDL) is a known risk factor for atherogenesis. This study aimed to reveal structural features of oxLDL present in human circulation related to atherosclerosis. When LDL was fractionated on an anion-exchange column, in vivo-oxLDL, dete
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 6, Pp 884-895 (2020)
J Lipid Res
J Lipid Res
Ceramides are the predominant lipids in the stratum corneum (SC) and are crucial components for normal skin barrier function. Although the composition of various ceramide classes in the human SC has been reported, that in mice is still unknown, despi
Autor:
Yoshihiro Shidoji, Yuki Tabata
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 5, Pp 778-789 (2020)
Journal of Lipid Research
Journal of Lipid Research
Geranylgeranoic acid (GGA) originally was identified in some animals and has been developed as an agent for preventing second primary hepatoma. We previously have also identified GGA as an acyclic diterpenoid in some medicinal herbs. Recently, we rep