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of 459
pro vyhledávání: ''
Autor:
Matthew J. Sweet, James E. B. Curson, David P. Fairlie, Kaustav Das Gupta, Robert Reid, Ashley Mansell, Denuja Karunakaran, Yizhuo Wang, Rishika Abrol, Divya Ramnath, Antje Blumenthal, Junxian Lim
Publikováno v:
Journal of Leukocyte Biology. 111:327-336
TLRs reprogram macrophage metabolism, enhancing glycolysis and promoting flux through the tricarboxylic acid cycle to enable histone acetylation and inflammatory gene expression. The histone deacetylase (HDAC) family of lysine deacetylases regulates
Autor:
Michael Z. Zulu, Ilhem Messaoudi, James D. Brien, Alexandria Dickson, Neil Tedeschi, Richard H. Scheuermann, Tara L. Steffen, Delia F. Tifrea, Kevin J. Maroney, Sarah L. George, Amelia K. Pinto, Yun Zhang, Amanda N. Pinski
Publikováno v:
Journal of Leukocyte Biology
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of coronavirus disease‐2019 (COVID‐19), a respiratory disease that varies in severity from mild to severe/fatal. Several risk factors for severe disease have
Autor:
Adam Godzik, Jiang Li, Xinru Qiu, Aarti Mittal, Meera G. Nair, Lukasz Jaroszewski, Jeff Bonenfant, Walter Klein
Publikováno v:
J Leukoc Biol
Systemic infections, especially in patients with chronic diseases, may result in sepsis: an explosive, uncoordinated immune response that can lead to multisystem organ failure with a high mortality rate. Patients with similar clinical phenotypes or s
Autor:
Christelle Le Dantec, Cristina Adela Iuga, Ioana-Ecaterina Pralea, Melanie Cornen, Wesley H. Brooks, Jacques-Olivier Pers, Hussam Saad, Tiffany Bergot, Adrian Tempescul, Anne Bordron, Delphine G. Bernard, Jean-Christophe Ianotto, Cristina Bagacean, Mihnea Zdrenghea, Christian Berthou, Yves Renaudineau
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, 2022, 111 (2), pp.313-325. ⟨10.1002/JLB.4HI0620-392R⟩
Journal of Leukocyte Biology, 2022, 111 (2), pp.313-325. ⟨10.1002/JLB.4HI0620-392R⟩
Chronic lymphocytic leukemia (CLL) is characterized by significant biologic and clinical heterogeneity. This study was designed to explore CLL B-cells’ proteomic profile in order to identify biologic processes affected at an early stage and during
Autor:
Patrycja Hoffmann, Neal S. Young, Amanda K. Ombrello, Shouguo Gao, Carrie Diamond, Naoki Watanabe, Zhijie Wu, Sai Batchu, Lemlem Alemu, Diego Quinones Raffo, Sachiko Kajigaya, Deborah L. Stone
Publikováno v:
Journal of Leukocyte Biology. 110:409-424
Deficiency of adenosine deaminase 2 (DADA2) is a rare autosomal recessive disease caused by loss-of-function variants in the ADA2 gene. DADA2 typically presents in childhood and is characterized by vasculopathy, stroke, inflammation, immunodeficiency
Autor:
Filip Van Nieuwerburgh, Hans Van Vlierberghe, Laurentijn Tilleman, Anne Hoorens, Lindsey Devisscher, Hannelore Van Eeckhoutte, Anja Geerts, Michael A. Lynes, Sander Lefere, Debby Laukens, Sanne Van Campenhout, Sarah Raevens
Publikováno v:
Journal of Leukocyte Biology. 111:123-133
Acetaminophen (APAP) intoxication is the foremost cause of drug-induced liver failure in developed countries. The only pharmacologic treatment option, N-acetylcysteine (NAC), is not effective for patients who are admitted too late and/or who have exc
Autor:
Réda Malek Hamidi, Rachida Khellafi, Ahmed Kadi, Reda Djidjik, Fawzi Derrar, Belgacem Mihi, Sarah Yasmine Rahali, Lilya Berkani, Asma Djidjeli, Ismahane Berkane, Dalila Mekideche, Zineb Larab, Lylia Kheddouci, Lydia Lamara Mahammad, A. Kheliouen, Brahim Belaid, Soraya Ayoub, Wafa Sayah, Fatma Merah, Mourad Ouali, Ines Allam, Merzak Gharnaout, Nouzha Zhor Lazli
Publikováno v:
Journal of Leukocyte Biology
The immune system plays a crucial role in the response against severe acute respiratory syndrome coronavirus 2 with significant differences among patients. The study investigated the relationships between lymphocyte subsets, cytokines, and disease ou
Publikováno v:
Journal of leukocyte biology. 112(5)
This study tested the hypothesis of gender bias in frequency of unconventional T cells. Unconventional T cells exist as minor subsets of T cells in peripheral blood. Despite their low number, they play a crucial role in various immune-mediated diseas
Autor:
Melanie A. Gasper, Nicholas Lejarcegui, Heather B. Jaspan, Helen Horton, Enock Havyarimana, Soren Gantt, Ana Gervassi, Elvis B. Kidzeru, Paul T. Edlefsen, Danica Shao, Kevin B. Urdahl
Publikováno v:
J Leukoc Biol
The role of Myeloid-Derived Suppressor Cells (MDSC) in infant immune ontogeny is unknown. Here, we evaluated MDSC frequency and relationship with infant vaccine responses throughout the first year of life in a prospective cohort study. Ninety-one Sou
Autor:
Jacqueline M. Ratter, H.J. Jansen, Rinke Stienstra, Hanne M. M. Rooijackers, Pleun C. M. van Poppel, Julia I P van Heck, Cees J. Tack
Publikováno v:
Journal of Leukocyte Biology, 110, 885-891
Journal of Leukocyte Biology, 110(5), 885-891
Journal of Leukocyte Biology 110 (2021) 5
Journal of Leukocyte Biology, 110, 5, pp. 885-891
Journal of Leukocyte Biology, 110(5), 885-891
Journal of Leukocyte Biology 110 (2021) 5
Journal of Leukocyte Biology, 110, 5, pp. 885-891
Contains fulltext : 245694.pdf (Publisher’s version ) (Closed access) Increased glycolysis is a metabolic trait of activated innate immune cells and supports functional changes including cytokine production. Insulin drives glycolysis in nonimmune c