Zobrazeno 1 - 10
of 58
pro vyhledávání: ''
Publikováno v:
Journal of Leukocyte Biology. 110:239-255
Follicular regulatory T (Tfr) cells are recently found to be a special subgroup of regulatory T (Treg) cells. Tfr cells play an important role in regulating the germinal center (GC) response, especially modulating follicular helper T (Tfh) cells and
Publikováno v:
Journal of Leukocyte Biology
Macrophages are key immune cells in the activation and regulation of immune responses. These cells are present in all tissues under homeostatic conditions and in many disease settings. Macrophages can exhibit a wide range of phenotypes depending on l
Autor:
Ramon Caballero, Edana Cassol, Duale Ahmed, Ashok Kumar, Simon Xin Min Dong, Hamza Ali, Angela M. Crawley, Jonathan B. Angel, Salma Iqbal, Niranjala Gajnayaka, Agatha Vranjkovic
Publikováno v:
Journal of Leukocyte Biology. 110:693-710
The inflammatory and anti-inflammatory Mϕs have been implicated in many diseases including rheumatoid arthritis, multiple sclerosis, and leprosy. Recent studies suggest targeting Mϕ function and activation may represent a potential target to treat
Publikováno v:
Journal of leukocyte biology
Human IFN-λ4 is expressed by only a subset of individuals who possess the ΔG variant allele at the dinucleotide polymorphism rs368234815. Recent genetic studies have shown an association between rs368234815 and different infectious and inflammatory
Autor:
Emily A. Weber, Sanjay B. Maggirwar, Pawel Kalinski, Vir B. Singh, Meera V. Singh, Sydney Simpson, Sumanun Suwunnakorn
Publikováno v:
J Leukoc Biol
In addition to their role in hemostasis, platelets store numerous immunoregulatory molecules such as CD40L, TGFβ, β2-microglobulin, and IL-1β and release them upon activation. Previous studies indicate that activated platelets form transient compl
Autor:
Hong Liu, Samantha Simpson, Seth Guller, Yong-Hong Zhang, Jiahui Ding, Paulomi Aldo, Jesper Petersen, Gil Mor, Lubna Pal, Michael J. Paidas, Yuan You, Gang Peng, Janina Kaislasuo, Ellen Løkkegaard, Ai-Hua Liao
Publikováno v:
J Leukoc Biol
Decidual macrophages are in close contact with trophoblast cells during placenta development, and an appropriate crosstalk between these cellular compartments is crucial for the establishment and maintenance of a healthy pregnancy. During different p
Autor:
Clément Barjon, Didier Pourquier, Florence Boissière-Michot, Nathalie Bonnefoy, Virginie Lafont, Evelyne Lopez-Crapez, Cécile Dejou, Ghita Chabab, Henri-Alexandre Michaud, William Jacot, Naoill Abdellaoui, Lucie Salvador-Prince
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, In press, ⟨10.1002/JLB.3MA0420-278RR⟩
Journal of Leukocyte Biology, Society for Leukocyte Biology, In press, ⟨10.1002/JLB.3MA0420-278RR⟩
γδ T cells contribute to the immune response against many cancers, notably through their powerful effector functions that lead to the elimination of tumor cells and the recruitment of other immune cells. However, their presence in the tumor microen
Publikováno v:
J Leukoc Biol
Allergies to food and environmental antigens have steeply grown to epidemic proportions. IgE antibodies are key mediators of allergic disease, including life-threatening anaphylaxis. There is now compelling evidence that one of the hallmarks of anaph
Autor:
Leo Koenderman, Guus P. Leijte, Nienke Vrisekoop, Niklas Bruse, Matthijs Kox, Marwan Hassani, Peter Pickkers
Publikováno v:
Journal of Leukocyte Biology, 108, 5, pp. 1665-1671
Journal of Leukocyte Biology, 108, 1665-1671
Journal of Leukocyte Biology, 108, 1665-1671
Contains fulltext : 229398.pdf (Publisher’s version ) (Open Access) Acute infection is characterized by eosinopenia. However, the underlying mechanism(s) are poorly understood and it is unclear whether decreased mobilization/production of eosinophi
Publikováno v:
Journal of Leukocyte Biology. 106:1233-1240
CD4+ Th cells play an important role in the development of rheumatoid arthritis (RA) by regulating adaptive immune response. As major subsets of CD4+ Th cells, Th17 cells can produce a large number of hallmark cytokines such as IL-17A and IL-17F, whi