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Publikováno v:
Journal of Leukocyte Biology. 111:391-400
Neutrophil extracellular traps (NETs)-mediated tissue damage is a hallmark in abdominal sepsis. Under certain conditions, microRNAs (miRs) can regulate protein expression and cellular functions. The aim of this study was to investigate the role of mi
Autor:
Sang-Ki Kim, Yu-Jin Lim, Kyoung-Oh Cho, Mee-Sun Yoon, Dong-Jun Shin, Soo-Hyeon Lee, Se-Cheol Park, Cheol-Jung Kim, Yeong-Bin Baek, Jun-Gyu Park, Jeong Won Hong
Publikováno v:
Journal of Leukocyte Biology. 111:439-450
Canine natural killer (NK) cells are large, granular lymphocytes that are neither B lymphocytes nor T lymphocytes. However, it has been reported that canine NK cells share some of the phenotypic characteristics of T lymphocytes, such as CD3 and CD5.
Autor:
Hugo Alberto Rodríguez-Ruiz, Berenice Illades-Aguiar, Walter David Cruz-Pineda, Isela Parra-Rojas, Inés Matia-García, Olga Lilia Garibay-Cerdenares
Publikováno v:
Journal of Leukocyte Biology. 111:197-208
Insulin is the hormone responsible for maintaining glucose homeostasis in the body, in addition to participating in lipid metabolism, protein synthesis, and the inhibition of gluconeogenesis. These functions are well characterized in the classic orga
Publikováno v:
J Leukoc Biol
The peritoneal cavity is a fluid filled space that holds most of the abdominal organs, including the omentum, a visceral adipose tissue that contains milky spots or clusters of leukocytes that are organized similar to those in conventional lymphoid t
Autor:
Daniel Prantner, Stefanie N. Vogel, David Spiegel, Katharina Richard, Shreeram C. Nallar, Kim D. Collins
Publikováno v:
J Leukoc Biol
The highly reactive compound methylglyoxal (MG) can cause direct damage to cells and tissues by reacting with cellular macromolecules. MG has been identified as a biomarker associated with increased sepsis-induced mortality. Patients undergoing septi
Autor:
Rafael M. Rezende, Gustavo B. Menezes, Maria Alice Freitas Lopes, Ariane Barros Diniz, Maísa Mota Antunes, Alan Moreira de Araujo, Camila Dutra Moreira de Miranda, Mateus Eustáquio Lopes, Brenda Naemi Nakagaki, Matheus Silvério Mattos, Kassiana Mafra, Débora Moreira Alvarenga
Publikováno v:
Journal of Leukocyte Biology. 108:1199-1213
Neutrophils were classically described as powerful effectors of acute inflammation, and their main purpose was assumed to be restricted to pathogen killing through production of oxidants. As consequence, neutrophils also may lead to significant colla
Autor:
Susan C. Menzies, Jessica Leung, Mahdis Monajemi, Rym Ben-Othman, Tobias R. Kollmann, Laura M. Sly, Bing Cai, Shera Fisk, Yvonne C. F. Pang, Jacob Rozmus
Publikováno v:
Journal of Leukocyte Biology. 106:863-877
This study tested the hypothesis that mucosa associated lymphoid tissue 1 (Malt1) deficiency causes osteoporosis in mice by increasing osteoclastogenesis and osteoclast activity. A patient with combined immunodeficiency (CID) caused by MALT1 deficien
Autor:
Naima Moustaid-Moussa, Luciano Ribeiro Filgueiras, Sonia Jancar, Theresa Ramalho, Latha Ramalingam, William T. Festuccia
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Serum levels of leukotriene-B4 (LTB4) are increased in type 1 diabetes (T1D) and it mediates systemic inflammation and macrophage reprogramming associated with this condition. Herein, we investigated the involvement of LTB4 in adiposity loss, hyperli
Autor:
Lohanna Palhinha, Lauar de Brito Monteiro, Jessica Aparecida da Silva Pereira, Pedro M. Moraes-Vieira
Publikováno v:
Journal of Leukocyte Biology. 106:703-716
Obesity is a pandemic disease affecting around 15% of the global population. Obesity is a major risk factor for other conditions, such as type 2 diabetes and cardiovascular diseases. The adipose tissue is the main secretor of leptin, an adipokine res
Autor:
Naoki Umeda, Makoto Makishima, Hiroyuki Nakashima, Kaori Endo-Umeda, Shuhji Seki, Shigeaki Kato
Publikováno v:
Journal of Leukocyte Biology. 106:791-801
The vitamin D receptor (VDR) is a nuclear receptor for the active form of vitamin D, 1α,25-dihydroxyvitamin D3, and regulates various physiologic processes, such as bone and calcium metabolism, cellular proliferation and differentiation, and immunit