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Autor:
Sang-Ki Kim, Yu-Jin Lim, Kyoung-Oh Cho, Mee-Sun Yoon, Dong-Jun Shin, Soo-Hyeon Lee, Se-Cheol Park, Cheol-Jung Kim, Yeong-Bin Baek, Jun-Gyu Park, Jeong Won Hong
Publikováno v:
Journal of Leukocyte Biology. 111:439-450
Canine natural killer (NK) cells are large, granular lymphocytes that are neither B lymphocytes nor T lymphocytes. However, it has been reported that canine NK cells share some of the phenotypic characteristics of T lymphocytes, such as CD3 and CD5.
Autor:
Hugo Alberto Rodríguez-Ruiz, Berenice Illades-Aguiar, Walter David Cruz-Pineda, Isela Parra-Rojas, Inés Matia-García, Olga Lilia Garibay-Cerdenares
Publikováno v:
Journal of Leukocyte Biology. 111:197-208
Insulin is the hormone responsible for maintaining glucose homeostasis in the body, in addition to participating in lipid metabolism, protein synthesis, and the inhibition of gluconeogenesis. These functions are well characterized in the classic orga
Autor:
Daniel Prantner, Stefanie N. Vogel, David Spiegel, Katharina Richard, Shreeram C. Nallar, Kim D. Collins
Publikováno v:
J Leukoc Biol
The highly reactive compound methylglyoxal (MG) can cause direct damage to cells and tissues by reacting with cellular macromolecules. MG has been identified as a biomarker associated with increased sepsis-induced mortality. Patients undergoing septi
Autor:
Rafael M. Rezende, Gustavo B. Menezes, Maria Alice Freitas Lopes, Ariane Barros Diniz, Maísa Mota Antunes, Alan Moreira de Araujo, Camila Dutra Moreira de Miranda, Mateus Eustáquio Lopes, Brenda Naemi Nakagaki, Matheus Silvério Mattos, Kassiana Mafra, Débora Moreira Alvarenga
Publikováno v:
Journal of Leukocyte Biology. 108:1199-1213
Neutrophils were classically described as powerful effectors of acute inflammation, and their main purpose was assumed to be restricted to pathogen killing through production of oxidants. As consequence, neutrophils also may lead to significant colla
Autor:
Naoki Umeda, Makoto Makishima, Hiroyuki Nakashima, Kaori Endo-Umeda, Shuhji Seki, Shigeaki Kato
Publikováno v:
Journal of Leukocyte Biology. 106:791-801
The vitamin D receptor (VDR) is a nuclear receptor for the active form of vitamin D, 1α,25-dihydroxyvitamin D3, and regulates various physiologic processes, such as bone and calcium metabolism, cellular proliferation and differentiation, and immunit
Publikováno v:
Journal of Leukocyte Biology. 101:217-226
Infiltrating myeloid cells in pregnant uteri play critical roles in the establishment of the placenta and maintenance of normal pregnancies. Their recruitment and proliferation are primarily mediated by the interactions of cytokines and chemokines se
Autor:
Yoshiaki Kitamura, Tomomi Kaneko-Goto, Weiping Chen, Ana Olivera, Juan Rivera, Richard L. Proia, Laurel D. Wright, Maria L. Allende, Yoshihiro Yoshihara
Publikováno v:
Journal of Leukocyte Biology. 94:1013-1024
Both genes and the environment are determinants in the susceptibility to allergies and may alter the severity of the disease. We explored whether an increase in the levels of the lipid mediator S1P in vivo, a condition found during allergic asthma, c
Autor:
Rohini Chennuri, Giamila Fantuzzi, Karla J. Castellanos, Robert J. Cabay, Davina H. Rhodes, Maria Pini, Eileen F. Grady, Andrew R. Hall
Publikováno v:
Journal of Leukocyte Biology. 91:957-966
Obesity increases severity of acute pancreatitis and risk of pancreatic cancer. Pancreatitis and obesity are associated with elevated IL-6, a cytokine involved in inflammation and tumorigenesis. We studied the role of IL-6 in the response of lean and
Publikováno v:
Journal of Leukocyte Biology. 88:475-481
Review discusses macrophages as the major extrahepatic source of IGF-1, and how a surge of CSF-1 production contributes to the control of postnatal growth and organ maturation. Growth hormone controls somatic growth in mammals by regulating the produ
Autor:
Valery Vera, Michael K. Connolly, Alan B. Frey, Dafna Bar-Sagi, Jon Mallen-St. Clair, Ashim Malhotra, Justin R. Henning, Junaid Ibrahim, George Miller, H. Leon Pachter, Andrea S. Bedrosian
Publikováno v:
Journal of Leukocyte Biology. 87:713-725
The expansion of distinct immune suppressive cells in the liver of tumor bearing hosts may bear on the propensity of patients with intra-abdominal cancers to develop liver metastases. The liver is the most common site of adenocarcinoma metastases, ev