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pro vyhledávání: '"133"'
Autor:
Deanna Guerra, Cees Vermeer, Federica Boraldi, Roberta Tiozzo, Tornmaso Trenti, Leon J. Schurgers, Daniela Quaglino, Giulia Annovi
Publikováno v:
Journal of Investigative Dermatology, 133(4), 946-954. Elsevier Science
Mineralization of elastic fibers in pseudoxanthoma elasticum (PXE) has been associated with low levels of carboxylated matrix gla protein (MGP), most likely as a consequence of reduced vitamin K (vit K) availability. Unexpectedly, vit K supplementati
Autor:
Zenzo Isogai, Seiya Matsui, Yosuke Yagi, Yoshiki Miyachi, Eri Muroga, Susumu Ikehara, Atsushi Utani, Shigehiko Suzuki, Motoko Naitoh
Publikováno v:
Journal of Investigative Dermatology. 133:386-393
The most distinctive feature of keloid is the extreme deposition of extracellular matrix, including collagens and proteoglycans (PGs). The focus of this study was the PG versican, which presumably defines keloid volume because of its ability to retai
Autor:
Martin Hrabé de Angelis, Helmut Fuchs, Jenny Li-Ying Huang, Mugdha Deo, Catherine D. Van Raamsdonk
Publikováno v:
J. Invest. Dermatol. 133, 49-58 (2013)
Mutations in neurofibromin (NF1) cause the dominant genetic disorder neurofibromatosis type 1. Neurofibromatosis is characterized by Schwann cell-based tumors and skin hyperpigmentation, resulting from both haploinsufficiency and loss of heterozygosi
Autor:
Geertrui Denecker, Barbara Gilbert, Leslie van der Fits, Jean-Pierre Hachem, Filip Van Nieuwerburgh, Bob Asselbergh, Riet De Rycke, Esther Hoste, Peter Vandenabeele, Wim Declercq, Errol P. Prens, Dieter Deforce
Publikováno v:
Journal of Investigative Dermatology, 133(3), 742-750. Nature Publishing Group
Caspase-14 is an important protease in the proper formation of a fully functional skin barrier. Newborn mice that are deficient in caspase-14 exhibit increased transepidermal water loss and are highly sensitive to UVB-induced photodamage. Decreased c