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Autor:
Tanja D. de Gruijl, Krista Ouwehand, Rik J. Scheper, Susan Gibbs, D. Oosterhoff, Melanie Breetveld
Publikováno v:
Journal of Investigative Dermatology, 131, 418-425. Nature Publishing Group
Ouwehand, K, Oosterhoff, D, Breetveld, M, Scheper, R J, de Gruijl, T D & Gibbs, S 2011, ' Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype. ', Journal of Investigative Dermatology, vol. 131, pp. 418-425 . https://doi.org/10.1038/jid.2010.336
Ouwehand, K, Oosterhoff, D, Breetveld, M, Scheper, R J, de Gruijl, T D & Gibbs, S 2011, ' Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype. ', Journal of Investigative Dermatology, vol. 131, pp. 418-425 . https://doi.org/10.1038/jid.2010.336
Langerhans cells (LCs) migrate after topical exposure of the skin to irritants, despite the supposed independence of irritant contact dermatitis from adaptive immunity. Whereas allergen-activated LCs are known to migrate to the draining lymph nodes (