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Autor:
FISH AJ, FREEDMAN SO
Publikováno v:
The Journal of investigative dermatology [J Invest Dermatol] 1964 Mar; Vol. 42, pp. 235-6.
Autor:
Kevin Sondenheimer, M. Majora, Jean Krutmann, Sonja Faßbender, Jennifer Schindler, Thomas Haarmann-Stemmann, Friederike V. Opitz, Marius Pollet, Heike Weighardt
Publikováno v:
Journal of Investigative Dermatology. 142:1183-1193
The transcription factor Hypoxia-Inducible Factor-1alpha (HIF-1a) regulates cellular metabolism under hypoxia but also immune responses and UVB-induced skin reactions. In keratinocytes, HIF-1a is an environmental sensor orchestrating the adaptation t
Autor:
John Ulf Rannug
Publikováno v:
Journal of Investigative Dermatology. 142:1758-1760
Autor:
Francine M. Foss, Kacie R. Carlson, Fatima N. Mirza, Shiela Umlauf, A.O. King, Julia M. Lewis, Yulia V. Surovtseva, Michael Girardi
Publikováno v:
Journal of Investigative Dermatology. 142:254-257
Autor:
Sophia Derdak, Veronika Mlitz, Karin Brigit Holthaus, Florian Ehrlich, Michael Mildner, Leopold Eckhart, Julia Lachner, Erwin Tschachler, Tanja Wagner
Publikováno v:
Journal of Investigative Dermatology. 141:2829-2837
The function of the skin as a barrier against a dry environment evolved in a common ancestor of terrestrial vertebrates such as mammals and birds. However, it is unknown which elements of the genetic program of skin barrier formation are evolutionari
Publikováno v:
J Invest Dermatol
The Ca(2+)-sensing receptor (CaSR) drives essential Ca(2+) and E-cadherin-mediated processes in the epidermis, including differentiation (Komuves et al., 2002), cell-to-cell adhesion (Tu et al., 2008) and epidermal barrier homeostasis in cells and yo
Publikováno v:
Journal of Investigative Dermatology. 141:2679-2689
Opsin-3 (OPN3) is a potential key regulator of human melanocyte melanogenesis. How OPN3-mediated regulation of melanocyte melanogenesis is triggered is largely unclear. TGFβ can inhibit the growth of human melanocytes and reduce melanin synthesis in
Publikováno v:
Journal of Investigative Dermatology. 141:2354-2368
Cutaneous squamous cell carcinomas (SCCs) are frequent heterogeneous tumors arising from sun-exposed regions of the skin and characterized by complex pathogenesis. HOPX is a member of the homeodomain-containing superfamily of proteins holding an atyp
Autor:
Yutaka Inaba, Meihong Da, Alexander Enk, Stephan Grabbe, Karsten Mahnke, Tobias Bopp, Sabine Ring
Publikováno v:
Journal of Investigative Dermatology. 141:2006-2017
The healing phase of contact hypersensitivity reactions is critically dependent on regulatory T cells (Tregs), but even the early inflammatory phase, that is, 6-24 hours after induction of a contact hypersensitivity reaction, is susceptible to Treg-m
Autor:
Jingling Zhao, Xusheng Liu, Lei Chen, Julin Xie, Ronghua Yang, Bin Shu, Yingbin Xu, Shaohai Qi, Shuai Yang
Publikováno v:
Journal of Investigative Dermatology. 141:1573-1584
The progression of diabetic complications does not halt despite the termination of hyperglycemia, suggesting a metabolic memory phenomenon. However, whether metabolic memory exists in and affects the healing of diabetic wounds, as well as the underly