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pro vyhledávání: '"133"'
Autor:
Martin Hrabé de Angelis, Helmut Fuchs, Jenny Li-Ying Huang, Mugdha Deo, Catherine D. Van Raamsdonk
Publikováno v:
J. Invest. Dermatol. 133, 49-58 (2013)
Mutations in neurofibromin (NF1) cause the dominant genetic disorder neurofibromatosis type 1. Neurofibromatosis is characterized by Schwann cell-based tumors and skin hyperpigmentation, resulting from both haploinsufficiency and loss of heterozygosi
Autor:
Rita Haapakoski, Terhi Savinko, Henrik Wolff, Harri Alenius, Antti Lauerma, Nanna Fyhrquist, Sari Lehtimäki, Piia Karisola
Publikováno v:
Journal of Investigative Dermatology; Vol 133
Toll-like receptors (TLRs) are pattern-recognition receptors that have a pivotal role as primary sensors of microbial products and as initiators of innate and adaptive immune responses. We investigated the role of TLR2, TLR3, and TLR4 activation duri
Autor:
Adam Calarese, Rachael A. Clark, Ying Jiang, Linda C. Wang, Chrysalyne D. Schmults, Victor Huang, Jessica E. Teague, A. Gehad, Mitra Dowlatshahi, Andrew DoRosario, Paul Nghiem, Jingwei Cheng, Carl F. Schanbacher, Manisha Thakuria
Publikováno v:
The Journal of investigative dermatology, vol 133, iss 7
The Journal of investigative dermatology
The Journal of investigative dermatology
Merkel cell carcinomas (MCCs) are rare but highly malignant skin cancers associated with a recently described polyomavirus. MCC tumors were infiltrated by T cells, including effector, central memory, and regulatory T cells. Infiltrating T cells showe
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