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pro vyhledávání: '"133"'
Autor:
Mathieu P Rodero, Herlina Y. Handoko, Graeme J. Walker, Geoffrey R. Hill, Blake Ferguson, Glen M. Boyle, Christian R. Engwerda, Kiarash Khosrotehrani, H. Konrad Muller
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2013, 133 (7), pp.1803-1812. ⟨10.1038/JID.2013.9⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2013, 133 (7), pp.1803-1812. ⟨10.1038/JID.2013.9⟩
Intermittent sunburns, particularly in childhood, are the strongest environmental risk factor for malignant melanoma (MM). In mice, a single neonatal UVR exposure induces MM, whereas chronic doses to adult mice do not. Neonatal UVR alters melanocyte
Autor:
Martin Hrabé de Angelis, Helmut Fuchs, Jenny Li-Ying Huang, Mugdha Deo, Catherine D. Van Raamsdonk
Publikováno v:
J. Invest. Dermatol. 133, 49-58 (2013)
Mutations in neurofibromin (NF1) cause the dominant genetic disorder neurofibromatosis type 1. Neurofibromatosis is characterized by Schwann cell-based tumors and skin hyperpigmentation, resulting from both haploinsufficiency and loss of heterozygosi