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Autor:
Cynthia M. Mack, Mary Anne M. Morgan, Michael J. Apostolakos, Michael S. Gough, Orren Wexler, Teodoro Bottiglieri, Erland Arning, Anthony P. Pietropaoli, Kathleen P. Doolin, Robert A. Mooney
Publikováno v:
Journal of Intensive Care Medicine. 33:37-47
Objective: Sepsis is characterized by microvascular dysfunction and thrombophilia. Several methionine metabolites may be relevant to this sepsis pathophysiology. S-adenosylmethionine (SAM) serves as the methyl donor for trans-methylation reactions. S