Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Xin WANG"'
Autor:
Xinxin Wang, Canrong Lu, Bo Wei, Shuo Li, Ziyu Li, Yingwei Xue, Yingjiang Ye, Zhongtao Zhang, Yihong Sun, Han Liang, Kai Li, Linghua Zhu, Zhichao Zheng, Yanbing Zhou, Yulong He, Fei Li, Xin Wang, Pin Liang, Hua Huang, Guoli Li, Xian Shen, Jiafu Ji, Yun Tang, Zekuan Xu, Lin Chen, on behalf of RESONANCE study group
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Evidence from Europe shows that perioperative chemotherapy may be beneficial for the treatment of locally advanced gastric cancer, but reliable and robust data is lacking. To rectify this, the phase 3 RESONANCE trial investigated the efficac
Externí odkaz:
https://doaj.org/article/2daba9815a064d7e91e91119d6b0691d
Autor:
Dawei Wu, Lingfeng Hu, Xin Wang, Yue Yu, Shuo-Peng Jia, Hui-Yao Huang, Zi-Wei Li, Jin-Feng Ma, Hai-Bo Zhu, Yu Tang, Ning Li
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-3 (2023)
Abstract The mRNA-based therapeutics have become the hot spot of biopharmaceutical industries in recent years. The landscape of this area is expanding from infectious disease to cancer, which needs to be summarized to provide data supports for indust
Externí odkaz:
https://doaj.org/article/37adef06005a4bc8aefd1e4cf7c4bc22
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract B-cell lymphoma is a group of hematological malignancies with high clinical and biological heterogeneity. The pathogenesis of B-cell lymphoma involves a complex interaction between tumor cells and the tumor microenvironment (TME), which is c
Externí odkaz:
https://doaj.org/article/e6fa06da16fd4e19bcad4286cca4d1bc
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Antibody-drug conjugates (ADCs) are a promising class of immunotherapies with the potential to specifically target tumor cells and ameliorate the therapeutic index of cytotoxic drugs. ADCs comprise monoclonal antibodies, cytotoxic payloads w
Externí odkaz:
https://doaj.org/article/a1d676023fa74fd1ad9f03bea4175d2f
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Harnessing the power of immune cells, especially T cells, to enhance anti-tumor activities has become a promising strategy in clinical management of hematologic malignancies. The emerging bispecific antibodies (BsAbs), which recruit T cells
Externí odkaz:
https://doaj.org/article/b6df204d45ef4945920c55a1620ce097
Autor:
Yun Liu, Honglian Wang, Xin Wang, Jiaqi Liu, Junjian Li, Xiang Wang, Yun Zhang, Zhigang Bai, Qinghua Zhou, Ying Wu, Yi Shen, Xiaoling Weng, Fatao Liu, Jiancheng Guo, Lijun Di, Olivier Gires, Zhongtao Zhang, Yiding Chen, Hongxia Wang
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)
Abstract Accurate interpretation of BRCA1/2 variants is critical for risk assessment and precise treatment of breast cancer (BC). Hence, the establishment of an ethnicity-based BRCA1/2 variant database of the Chinese population is of paramount import
Externí odkaz:
https://doaj.org/article/62072e30c65c45f29c9cf8d94a5395cd
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract The aberrant Wnt/β-catenin signaling pathway facilitates cancer stem cell renewal, cell proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy response. Accumulated investigations highlight the therapeut
Externí odkaz:
https://doaj.org/article/798cf09526434b7584e2a6bfc2fb1797
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract With covalently closed circular structures, circular RNAs (circRNAs) were once misinterpreted as by-products of mRNA splicing. Being abundant, stable, highly conserved, and tissue-specific, circRNAs are recently identified as a type of regul
Externí odkaz:
https://doaj.org/article/0c816636446b488f9eb60bb4db97d954
Autor:
Xiangxiang Zhou, Na Chen, Hongzhi Xu, Xiaoming Zhou, Jianhong Wang, Xiaosheng Fang, Ya Zhang, Ying Li, Juan Yang, Xin Wang
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Background Hippo-Yes-associated protein (YAP) signaling is a key regulator of organ size and tumorigenesis, yet the underlying molecular mechanism is still poorly understood. At present, the significance of the Hippo-YAP pathway in diffuse l
Externí odkaz:
https://doaj.org/article/57b7d0326f6f49e8b14b840f932665b0
Autor:
Fahmin Basher, Payal Dhar, Xin Wang, Derek A. Wainwright, Bin Zhang, Jeffrey Sosman, Zhe Ji, Jennifer D. Wu
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract Background Melanoma patients who have detectable serum soluble NKG2D ligands either at the baseline or post-treatment of PD1/PDL1 blockade exhibit poor overall survival. Among families of soluble human NKG2D ligands, the soluble human MHC I
Externí odkaz:
https://doaj.org/article/adb45e608f324f5f9ccd09e0e52979ea