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Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background SIRT1 expression and Notch1 signaling have been implicated in tumorigenesis in many cancers, but their association with survival in breast cancer has not been determined. The purpose of this study was to assess the possible prognostic valu
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background Breast cancer patients with positive estrogen receptor (ER) have a better prognosis. However, no prognostic miRNA signature was reported in the ER-positive breast cancer. The aim of the study was to identify and assess the prognostic signi
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background Breast cancer is the most fatal malignant cancer among women, the conventional therapeutic modalities of it are limited. Morusin possesses cytotoxicity against some cancer cells in vitro. The purpose of this study is to test the growth inh
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background Many long non-coding RNAs(lncRNAs) have been found to be a good marker for several tumors. Using lncRNA-mining approach, we aimed to identify lncRNA expression signature that can predict breast cancer patient survival. Methods We performed
Autor:
Pierpaolo Gullo, Maurizio Costantini, Ernesto Maria Buccheri, Antonio Varanese, Roy De Vita, Marcello Pozzi, Giovanni Zoccali
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Introduction In women with macromastia, a type IV skin sparing mastectomy is often required to achieve an aesthetically pleasing reconstruction. The introduction of “skin-reducing mastectomy”, which inserts a permanent prosthetic device into a la
Autor:
Paolo Anibaldi, Valerio D'Orazi, Francesco Monteleone, Merola R, Silvia Iacobelli, Giulia Anna Follacchio, Giuseppe De Vincentis, Vittorio Pasta, Massimo Monti
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background The spread of mammographic screening programs has allowed an increasing amount of early breast cancer diagnosis. A modern approach to non-palpable breast lesions requires an accurate intraoperative localization, in order to achieve a compl
Autor:
Yuxuan Wang, Yongjie Xu, Genze Shao, Luzheng Xu, Shucong Meng, Jingyu Kuang, Xiaozhen Wang, Limei Guo, Li Li, Liandi Lei, Yanrong Su
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background Epithelial-mesenchymal transition (EMT) is a crucial step for solid tumor progression and plays an important role in cancer invasion and metastasis. RNF8 is an ubiquitin E3 ligase with RING domain, and plays essential roles in DNA damage r
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background One-third of estrogen (ER+) and/or progesterone receptor-positive (PGR+) breast tumors treated with Tamoxifen (TAM) do not respond to initial treatment, and the remaining 70% are at risk to relapse in the future. Estrogen-related receptor
Autor:
Yu-Wei Xia, Feng Yang, Jian Qin Michael Yu, Bao-Hong Liu, Xiao-Lin Lin, Guo-Hui Ding, Ying-Chun Xu, Hong-Xia Wang, Jian-Jun Liu, Lei Tang, Zhi-Qiang Yin, Yue Ma
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Purpose The aim of this study was to evaluate the ability of a 41-gene signature derived from breast cancer stem cells (BCSCs) to estimate the risk of metastasis and survival in breast cancer patients. Methods The centroid expression of the 41-gene s
Autor:
Stanley N.C. Anyanwu
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 27, Iss 1, p 17 (2008)
Journal of Experimental & Clinical Cancer Research, Vol 27, Iss 1, p 17 (2008)
Background Third world breast cancer is characterized by late presentation, occurrence at relatively young ages and dismal mortality. This poor outcome has encouraged patients to patronize quacks and alternative healers. Public control measures have