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Autor:
Paola Lovato, Anders Woetmann, Hanne Norsgaard, Minna Lund Tiirikainen, Luis F. Santamaria-Babí
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Tiirikainen, M L, Woetmann, A, Norsgaard, H, Santamaria-Babí, L F & Lovato, P 2020, ' Ex vivo culture of lesional psoriasis skin for pharmacological testing ', Journal of Dermatological Science, vol. 97, no. 2, pp. 109-116 . https://doi.org/10.1016/j.jdermsci.2019.12.010
Universidad de Barcelona
Tiirikainen, M L, Woetmann, A, Norsgaard, H, Santamaria-Babí, L F & Lovato, P 2020, ' Ex vivo culture of lesional psoriasis skin for pharmacological testing ', Journal of Dermatological Science, vol. 97, no. 2, pp. 109-116 . https://doi.org/10.1016/j.jdermsci.2019.12.010
Background Psoriasis is a chronic, inflammatory skin disorder resulting from a complex interplay between immune and skin cells via release of soluble mediators. While a lot is known about the molecular mechanisms behind psoriasis pathogenesis, there
Publikováno v:
Journal of Dermatological Science. 94:259-265
Systemic sclerosis (SSc) is a multisystem connective tissue disease characterized by three cardinal pathological features, such as autoimmunity/inflammation, vasculopathy and extensive organ fibrosis. Therefore, numerous interests have been put on th
Autor:
Haruka Kuriyama, Yosuke Kubo, Tatsuaki Iwama, Satoshi Fukushima, Satoru Senju, Hisashi Kanemaru, Toshihiro Kimura, Hironobu Ihn, Takayuki Ishibashi, Yasushi Uemura, Satoshi Nakahara, Shinichi Masuguchi, Rong Zhang, Azusa Miyasita, Tetsuya Nakatsura, Satoru Mizuhashi
Publikováno v:
Journal of dermatological science. 102(2)
Publikováno v:
Journal of dermatological science. 102(2)
Background The involvement of the nerve in psoriasis development was suggested by sporadic case reports. Objectives To provide multiple evidence for the nerve in psoriasis development with a retrospective case review, a literature review and a mouse-
Autor:
Akiko Sekiguchi, Mari Hosoi, Akihiko Uchiyama, Yuta Inoue, Chisako Fujiwara, Yoko Yokoyama, Sahori Yamazaki, Sei-ichiro Motegi, Syahla Nisaa Amalia, Sachiko Ogino, Hritu Baral, Osamu Ishikawa, Ryoko Torii
Publikováno v:
Journal of dermatological science. 101(1)
Background Psoriasis is a multifactorial disease arises from a complex interaction of genetics, immune system, and environmental aspects. IL-23/Th17 immune axis has been considered as a primary modulator in psoriasis. In addition, several findings im
Autor:
Panpan Liu, Honglin Wang, Juan Su, Wangqing Chen, Shuang Zhao, Yehong Kuang, Yijing He, Xiang Chen, Menglin Chen, Jie Li, Juan Tao, Wu Zhu, Jianglin Zhang, Mingliang Chen
Publikováno v:
Journal of Dermatological Science. 89:233-240
BACKGROUND Psoriasis is a chronic inflammatory disease characterized by epidermal hyperplasia and increased T cell infiltration. Cytotoxic T lymphocyte antigen-4 (CTLA-4) is a key factor that affects T cell function and immune response. However, whet
Autor:
Junzo Hisatsune, Shunsuke Takahagi, Michihiro Hide, Masachika Saino, Yoshie Niitsu, Masaya Moriwaki, Kazumasa Iwamoto, Motoyuki Sugai
Publikováno v:
Journal of Dermatological Science. 88:271-279
Background Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. The skin of patients with AD presents as a disbalance of the microbiome with a strong colonization by Staphylococcus aureus, which positively correlates w
Autor:
Hiroo Hata, Yasuhiro Fujisawa, Hisako Okuhira, Atsushi Otsuka, Takeru Funakoshi, Keisuke Imafuku, Ryota Tanaka, Masahiko Gosho, Megumi Aoki, Kei Yamaguchi, Ikuko Hirai, Taku Fujimura, Yuki Yamamoto, Shigeto Matsushita, Sadanori Furudate, Koji Yoshino, Yumi Nonomura
Publikováno v:
Journal of Dermatological Science. 88:225-231
Background Although nivolumab significantly prolongs survival of metastatic melanoma, about 10% of patients experience severe, even fatal immune-related adverse events (irAEs). Biomarkers to predict irAEs are, therefore, of great interest. Objective
Autor:
Michael Soeberdt, Ulrich Knie, Christoph Abels, Stephan Dähnhardt-Pfeiffer, Judit Szabó-Papp, Tamás Bíró, Attila Oláh
Publikováno v:
Journal of Dermatological Science. 88:67-77
Background Atopic eczema (AE) is a chronic inflammatory and pruritic skin disease. There is still an unmet need for topical anti-inflammatory and anti-pruritic substances exhibiting an excellent safety profile. The endocannabinoid system is known to
Autor:
Karsten Mahnke, Sabine Ring, Alexander Enk, A. Neuberger, Jürgen Schrader, Cinthia Silva-Vilches
Publikováno v:
Journal of Dermatological Science. 87:292-299
Background Application of haptens to the skin induces release of immune stimulatory ATP into the extracellular space. This “danger” signal can be converted to immunosuppressive adenosine (ADO) by the action of the ectonucleotidases CD39 and CD73,