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Autor:
Rachael Wojcik, Erica Westphal, Michelle Rainka, Jessica Greger, Emily Lewandowski, Traci Aladeen, Horacio Capote
Publikováno v:
Journal of Clinical Psychopharmacology. 41:5-12
PURPOSE/BACKGROUND Extensive research has been conducted comparing the metabolic characteristics of older second-generation antipsychotics (SGAs); minimal data exist comparing the long-term metabolic effects of SGAs approved in the last 10 years. MET
Publikováno v:
Journal of Clinical Psychopharmacology. 39:238-242
Background Lithium in the form of lithium carbonate (Li2CO3) has become one of the most effective and widely prescribed drugs for mood stabilization. However, lithium has adverse effects on renal tubular functions, such as decreased concentrating fun
Autor:
Cynthia X. Ma, Eric J. Lenze, Tahir Rahman, Michael D. Yingling, Benoit H. Mulsant, Cory Patrick, Charles F. Reynolds, Ginger E. Nicol, Sarah M. Hartz
Publikováno v:
Journal of clinical psychopharmacology. 41(1)
Background Antipsychotic drugs are well established to alter serum prolactin levels, often resulting in adverse effects including amenorrhea, galactorrhea, osteoporosis, and loss of libido. There is growing preclinical evidence that prolactin-elevati
Autor:
Mahmut Oğuz Ulusoy, Selen Işık-Ulusoy
Publikováno v:
Journal of clinical psychopharmacology. 41(1)
Purpose Several studies have previously reported the association between dry eye and depression along with the treatment of depression. The aim of this study was to investigate the effects of different antidepressant drugs on tear parameters in patie
Autor:
Rhonda A Robeel, Glenn Catalano, Susan K. Schultz, Deborah L Sanchez, Maria C. Catalano, Grace A Cheney, Benjamin C. Spurling
Publikováno v:
Journal of clinical psychopharmacology. 40(4)
Purpose Antidepressant augmentation strategies for treatment-resistant depression (TRD) are discussed here with an analysis of patient out-of-pocket costs for various medications. The choice of agent ranges from newer atypical antipsychotics (aripipr
Publikováno v:
Journal of clinical psychopharmacology. 39(6)
Background The negative symptoms of schizophrenia pose a heavy burden on patients and relatives and represent an unmet therapeutic need. The observed association of negative symptoms with impaired reward system function has stimulated research on pro
Autor:
Alyson Nakamura, Duc M. Nguyen, E. Sherwood Brown, Alexandra Kulikova, Michael A. Yassa, Erin Van Enkevort, Jared M. Roberts, Nicholas J. Tustison, Elena I. Ivleva
Publikováno v:
J Clin Psychopharmacol
Journal of clinical psychopharmacology, vol 39, iss 6
Journal of clinical psychopharmacology, vol 39, iss 6
PURPOSE/BACKGROUND: Glucocorticoids are a class of hormones that include naturally occurring cortisol and corticosterone, as well as prescription drugs commonly used to manage inflammatory, autoimmune, and allergic conditions. Adverse effects, includ
Autor:
Joan Gu, Manisha Madhoo, Matthew Dauphin, Olga Brawman-Mintzer, Roger S. McIntyre, Rajnish Mago, Dan V. Iosifescu, Brooke Geibel, Elias Sarkis, Cynthia Richards, Richard H. Weisler
Publikováno v:
Journal of Clinical Psychopharmacology
Supplemental digital content is available in the text.
Purpose/Background Psychostimulant augmentation is considered a potential treatment strategy for individuals with major depressive disorder who do not adequately respond to antidepressant mo
Purpose/Background Psychostimulant augmentation is considered a potential treatment strategy for individuals with major depressive disorder who do not adequately respond to antidepressant mo
Publikováno v:
Journal of clinical psychopharmacology. 39(5)
Purpose Increased cannabis use and recent drug approvals pose new challenges for avoiding drug interactions between cannabis products and conventional medications. This review aims to identify drug-metabolizing enzymes and drug transporters that are
Autor:
Haoyang Lu, Shuhua Deng, Ming Zhang, Xiuqing Zhu, Zhanzhang Wang, Xiao-Jia Ni, Huan Peng, Yue-Feng Zhang, Yuguan Wen, Dewei Shang, Yuqing Chen, Jinqing Hu
Publikováno v:
Journal of Clinical Psychopharmacology. 38:129-133
PURPOSE/BACKGROUND Blonanserin is a novel antipsychotic drug approved for the treatment of schizophrenia in East Asia. The main objective of the present study was to investigate the effect of alcohol on the pharmacokinetic properties of blonanserin a