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Publikováno v:
Journal of Clinical Psychopharmacology. 39:238-242
Background Lithium in the form of lithium carbonate (Li2CO3) has become one of the most effective and widely prescribed drugs for mood stabilization. However, lithium has adverse effects on renal tubular functions, such as decreased concentrating fun
Autor:
Robert L. Findling, Nora K. McNamara, Vivian Kafantaris, Jean A. Frazier, Perdita Taylor-Zapata, Jacqui Lingler, Cornelia B. Landersdorfer, Robert A. Kowatch, Mani N. Pavuluri, William J. Jusko, Jon McClellan, Linmarie Sikich, Jon E. Faber
Publikováno v:
Journal of Clinical Psychopharmacology. 30:404-410
Bipolar I disorder (BP-I) in children and adolescents is associated with substantive psychosocial dysfunction and human suffering [1, 2]. Safe and effective treatments are needed to reduce symptomatology and improve quality of life for the vulnerable
Publikováno v:
Journal of Clinical Psychopharmacology. 19:240-245
Forty bipolar depressed inpatients underwent three consecutive cycles of total sleep deprivation (TSD). At the beginning of the study, 20 patients were free of psychotropic drugs and 20 had been receiving Lithium medication for at least 6 months. Moo
Publikováno v:
Journal of Clinical Psychopharmacology. 18:384-389
One hundred patients who had attempted suicide before commencing lithium prophylaxis were followed up. Outcome was analyzed in terms of attempted or completed suicide after a mean of 10 years since admission to the lithium clinics. Of 10 patients who
Publikováno v:
Journal of Clinical Psychopharmacology. 17:44-48
The objective of this study was to compare the onset, rate of antidepressant (AD) response, and treatment outcome of depressed patients treated for 5 weeks with either the concomitant administration of the tricyclic AD desipramine (DMI) and lithium c
Publikováno v:
Journal of clinical psychopharmacology. 24(2)
The acute and chronic effects of lithium carbonate administration at therapeutic blood levels on peripheral noradrenergic activity and sympathetic responses to alpha(2) adrenoceptor blockade were examined in 10 medically and psychiatrically healthy v
Autor:
Pál Czobor, Geraldine Dacpano, Nancy Richardson, Thomas B. Cooper, Manuel Trujillo, Ivan Tuma, J. A. N. Volavka, James C.-Y. Chou
Publikováno v:
Journal of clinical psychopharmacology. 21(4)
In this study, the authors examined the relationship between steady-state haloperidol blood levels and clinical response in patients with acute psychotic mania. Fifty-four inpatients with acute mania were randomly assigned to receive either haloperid
Publikováno v:
Journal of clinical psychopharmacology. 18(3)
Prescription doses of nonsteroidal antiinflammatory agents have been shown to decrease clearance and increase plasma concentrations of lithium. This study was designed to evaluate whether over-the-counter (OTC) doses of naproxen sodium or acetaminoph
Publikováno v:
Journal of clinical psychopharmacology. 17(3)
The pharmacokinetics of lithium was studied in 16 manic-depressive Chinese adults who were on lithium therapy in Hong Kong. A two-compartment open model was used to describe the plasma data obtained. The steady-state volume of distribution and total
Publikováno v:
Journal of clinical psychopharmacology. 17(2)
Twenty-two patients affected by bipolar or schizoaffective disorder, in whom carbamazepine was added to lithium after recurrence when on maintenance with lithium alone, were followed up prospectively for 2 to 13 years. The number of episodes, hospita