Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Christoph Engel"'
Autor:
Judith Balmaña, Douglas F. Easton, Adeline Cuggia, Kenneth Offit, Heli Nevanlinna, Judy Garber, Florentia Fostira, Kelly A. Metcalfe, Jana Soukupova, Carlo Tondini, Orland Diez, George Zogopoulos, James Scarth, Marketa Janatova, Tuya Pal, Mark E. Robson, James E. Redman, Laura Ottini, Patrick Concannon, Ann S.G. Lee, Åke Borg, Anders Kvist, Sandra Schneider, Valentina Silvestri, Christoph Engel, Rachel Silva-Smith, Antoine De Pauw, Tu Nguyen-Dumont, Inga Plaskocinska, Katherine L. Nathanson, Hans Ehrencrona, Susan J. Ramus, Rita K. Schmutzler, Craig Luccarini, Mitul Shah, Sophia George, Goska Leslie, Jeffrey N. Weitzel, Irene Konstantopoulou, Carl Blomqvist, William D. Foulkes, Georgia Chenevix-Trench, Marc Tischkowitz, Thomas van Overeem Hansen, Pei Sze Ng, Kathleen Claes, Ellen L. Goode, Olufunmilayo I. Olopade, Sarah M. Nielsen, Andy C. H. Lee, Melissa C. Southey, Ramunas Janavicius, Jill S. Dolinsky, Alfons Meindl, Paolo Peterlongo, Julie O. Culver, Kristiina Aittomäki, Robert Winqvist, Alison H. Trainer, Tuomas Heikkinen, Paolo Radice, David E. Goldgar, Florian Obermair, Marie E. Wood, Jonine L. Bernstein, Sook-Yee Yoon, Paul D.P. Pharoah, Christopher R. Hake, Claude Houdayer, Irene L. Andrulis, Aaron Elliott, Zaki El-Haffaf, Petra Kleiblova, Jukka S. Moilanen, Judith Hurley, Antonis C. Antoniou, Siranoush Manoukian, Fergus J. Couch, Anne-Bine Skytte, Susan L. Neuhausen, Gary Unzeitig, D. Gareth Evans, Eamonn R. Maher, John L. Hopper, Rachel McFarland, James A. G. Whitworth, Judith Penkert, Julian Barwell, Susan M. Domchek, Zdenek Kleibl, Leila Dorling, Lisa Golmard, Peter Ang, Brennan Decker, Cheng Har Yip, Nur Aishah Taib, Vilius Rudaitis, Julian Adlard, Xin Yang, Jamie Allen, Lydia Usha, Francesca Damiola, Amal Yussuf, Katri Pylkäs, Alicja Doroszuk, Eric Hahnen, Muriel A. Adank, Karen A. Pooley, Soo Hwang Teo, Kristie Bobolis, Paul A. James, Alison M. Dunning, Holly LaDuca, Stephen B. Gruber, Wendy McKinnon, Fabienne Lesueur, Lucy Side, Arto Mannermaa, Thomas P. Slavin
Publikováno v:
Yang, X, Leslie, G, Doroszuk, A, Schneider, S, Allen, J, Decker, B, Dunning, A M, Redman, J, Scarth, J, Plaskocinska, I, Luccarini, C, Shah, M, Pooley, K, Dorling, L, Leei, A, Adank, M A, Adlard, J, Aittomäki, K, Andrulis, I L, Ang, P, Barwell, J, Bernstein, J L, Bobolis, K, Borg, Å, Blomqvist, C, Claes, K B M, Concannon, P, Cuggia, A, Culver, J O, Damiola, F, De Pauw, A, Diez, O, Dolinsky, J S, Domchek, S M, Engel, C, Evans, D G, Fostira, F, Garber, J, Golmard, L, Goode, E L, Gruber, S B, Hahnen, E, Hake, C, Heikkinen, T, Hurley, J E, Janavicius, R, Kleibl, Z, Kleiblova, P, Konstantopoulou, I, Kvist, A, Laduca, H, Lee, A S G, Lesueur, F, Maher, E R, Mannermaa, A, Manoukian, S, McFarland, R, McKinnon, W, Meindl, A, Metcalfe, K, Taib, N A M, Moilanen, J, Nathanson, K L, Neuhausen, S, Ng, P S, Nguyen-Dumont, T, Nielsen, S M, Obermair, F, Offit, K, Olopade, O I, Ottini, L, Penkert, J, Pylkäs, K, Radice, P, Ramus, S J, Rudaitis, V, Side, L, Silva-Smith, R, Silvestri, V, Skytte, A B, Slavin, T, Soukupova, J, Tondini, C, Trainer, A H, Unzeitig, G, Usha, L, Van Overeem Hansen, T, Whitworth, J, Wood, M, Yip, C H, Yoon, S Y, Yussuf, A, Zogopoulos, G, Goldgar, D, Hopper, J L, Chenevix-Trench, G, Pharoah, P, George, S H L, Balmaña, J, Houdayer, C, James, P, El-Haffaf, Z, Ehrencrona, H, Janatova, M, Peterlongo, P, Nevanlinna, H, Schmutzler, R, Teo, S H, Robson, M, Pal, T, Couch, F, Weitzel, J N, Elliott, A, Southey, M, Winqvist, R, Easton, D F, Foulkes, W D, Antoniou, A C & Tischkowitz, M 2020, ' Cancer risks associated with germline PALB2 pathogenic variants : An international study of 524 families ', Journal of Clinical Oncology, vol. 38, no. 7, pp. 674-685 . https://doi.org/10.1200/JCO.19.01907
PURPOSE To estimate age-specific relative and absolute cancer risks of breast cancer and to estimate risks of ovarian, pancreatic, male breast, prostate, and colorectal cancers associated with germline PALB2 pathogenic variants (PVs) because these ri
Autor:
Verena Steinke, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Rolf H. Sijmons, Encarna B. Gomez Garcia, Markus Loeffler, Wolff Schmiegel, Elke Holinski-Feder, Reinhard Buettner, Frederik J. Hes, Christoph Engel, Hans K. Schackert, Nils Rahner, Gabriela Moeslein, Theo A. M. van Os, Fred H. Menko, Timm O. Goecke, Tom G.W. Letteboer, Irma Kluijt, Hans F. A. Vasen, Heike Goergens, Wolfgang Dietmaier, Peter Propping, Anja Wagner
Publikováno v:
Journal of Clinical Oncology, 30(35), 4409-4415. American Society of Clinical Oncology
Journal of Clinical Oncology, 30, 35, pp. 4409-15
Journal of Clinical Oncology, 30(35), 4409-4415. AMER SOC CLINICAL ONCOLOGY
Journal of clinical oncology, 30(35), 4409-4415. American Society of Clinical Oncology
Engel, C, Loeffler, M, Steinke, V, Rahner, N, Holinski-Feder, E, Dietmaier, W, Schackert, H K, Goergens, H, Doeberitz, M V, Goecke, T O, Schmiegel, W, Buettner, R, Moeslein, G, Letteboer, T G W, Garcia, E G, Hes, F J, Hoogerbrugge, N, Menko, F H, van Os, T A M, Sijmons, RH, Wagner, A, Kluijt, I, Propping, P & Vasen, H F A 2012, ' Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome ', Journal of Clinical Oncology, vol. 30, no. 35, pp. 4409-4415 . https://doi.org/10.1200/JCO.2012.43.2278
Journal of Clinical Oncology, 30, 4409-15
Journal of Clinical Oncology, 30, 35, pp. 4409-15
Journal of Clinical Oncology, 30(35), 4409-4415. AMER SOC CLINICAL ONCOLOGY
Journal of clinical oncology, 30(35), 4409-4415. American Society of Clinical Oncology
Engel, C, Loeffler, M, Steinke, V, Rahner, N, Holinski-Feder, E, Dietmaier, W, Schackert, H K, Goergens, H, Doeberitz, M V, Goecke, T O, Schmiegel, W, Buettner, R, Moeslein, G, Letteboer, T G W, Garcia, E G, Hes, F J, Hoogerbrugge, N, Menko, F H, van Os, T A M, Sijmons, RH, Wagner, A, Kluijt, I, Propping, P & Vasen, H F A 2012, ' Risks of Less Common Cancers in Proven Mutation Carriers With Lynch Syndrome ', Journal of Clinical Oncology, vol. 30, no. 35, pp. 4409-4415 . https://doi.org/10.1200/JCO.2012.43.2278
Journal of Clinical Oncology, 30, 4409-15
Purpose Patients with Lynch syndrome are at high risk for colon and endometrial cancer, but also at an elevated risk for other less common cancers. The purpose of this retrospective cohort study was to provide risk estimates for these less common can
Autor:
Matthias Kloor, Karsten Schulmann, Judith Kuhlkamp, Robert Hueneburg, Stefan Aretz, Christian Pox, Claudia Perne, Christoph Engel, Elke Holinski-Feder, Verena Steinke-Lange, Nils Rahner, Monika Morak, Deepak Vangala, Swetlana Ladigan, Hans K. Schackert, Christian P. Strassburg, Reinhard Büttner, Stefanie Holzapfel, Wolff Schmiegel, Markus Loeffler
Publikováno v:
Journal of Clinical Oncology. 36:1555-1555
1555Background: Small bowel carcinomas (SBC) account for less than 5% of all gastrointestinal malignancies in the general population. However in patients with Lynch-Syndrome (LS) the life-time-risk...
Autor:
Jacob Nattermann, Christian Pox, Stefan Aretz, Nils Rahner, Wolff Schmiegel, Christian P. Strassburg, Monika Morak, Judith Kuhlkamp, Swetlana Ladigan, Christoph Engel, Markus Loeffler, Robert Hueneburg, Deepak Vangala, Karsten Schulmann, Hans K. Schackert, Elke Holinski-Feder, Verena Steinke-Lange, Matthias Kloor, Reinhard Büttner, Claudia Perne
Publikováno v:
Journal of Clinical Oncology. 36:1522-1522
1522Background: Gastric cancer (GC) is the second most common non-gynecologic malignancy in patients with LS. Due to an absence of prospective randomized data, the value of esophago-gastro-duodenos...
Autor:
Markus Loeffler, Monika Graeser, Carolin Nestle-Kraemling, Mohammad Zaino, Marion Kiechle, Sabine Preisler-Adams, Karin Kast, Dorothea Gadzicki, Norbert Arnold, Christoph Engel, Astrid Bechtold, Ursula G. Froster, Rita K. Schmutzler, Dominic Varga, Alfons Meindl, Ulrich Bick, B. Schlehe, Kerstin Rhiem
Publikováno v:
Journal of Clinical Oncology. 27:5887-5892
Purpose To estimate the risk for contralateral breast cancer in members of BRCA1- and BRCA2-positive families and to determine predictive risk factors. Patients and Methods A retrospective, multicenter, cohort study was performed from 1996 until 2008
Autor:
Christoph Engel, Johannes Gebert, Gabriela Moeslein, Karsten Schulmann, Hans K. Schackert, Wolff Schmiegel, Constanze Pagenstecher, Timm O. Goecke, Josef Rueschoff, Elke Holinski-Feder, Stefan Krüger, Nicolaus Friedrichs, Matthias Kloor, Markus Loeffler, Elisabeth Mangold, Erdmute Kunstmann, Holger Vogelsang, Gisela Keller, Peter Propping, Wolfgang Dietmaier
Publikováno v:
Journal of Clinical Oncology. 24:4285-4292
Purpose Lynch syndrome is linked to germline mutations in mismatch repair genes. We analyzed the genotype-phenotype correlations in the largest cohort so far reported. Patients and Methods Following standard algorithms, we identified 281 of 574 unrel
Autor:
Josef Rüschoff, Markus Loeffler, Stefan Krüger, Karsten Schulmann, Christoph Engel, Johannes Gebert, Constanze Pagenstecher, Jens Plaschke, Magnus von Knebel Doeberitz, Elke Holinski-Feder, Hans K. Schackert, Elisabeth Mangold, Gabriela Moeslein
Publikováno v:
Journal of Clinical Oncology. 22:4486-4494
Purpose The aim of the study was the analysis of the involvement and phenotypic manifestations of MSH6 germline mutations in families suspected of hereditary nonpolyposis colorectal cancer (HNPCC). Patients and Methods Patients were preselected among
Publikováno v:
Journal of Clinical Oncology. 28:e607-e608
Autor:
Wolff Schmiegel, Sven Koepnick, Karsten Schulmann, Brigitte Royer-Pokora, Christoph Engel, C. Bernhardt, Elke Holinski-Feder, Hans K. Schackert, Reinhard Büttner, Magnus von Knebel Doeberitz, Verena Steinke
Publikováno v:
Journal of Clinical Oncology. 30:3550-3550
3550 Background: Previous studies showed conflicting results regarding the value of ACT in MSI-H CC. A recent study reported differential benefits from 5-FU-based ACT comparing suspected sporadic vs suspected hereditary MSI-H CC. We sought to evaluat
Autor:
Nina Ditsch, Dorothee Speiser, Wolfgang Janni, S Briest, Monika Graeser, Alfons Meindl, Marion Kiechle, Christoph Mundhenke, Rita K. Schmutzler, J. Tio, Kerstin Rhiem, Dorothea Gadzicki, M. Golatta, R. Kreienberg, A. Honig, Karin Kast, Christoph Engel
Publikováno v:
Journal of Clinical Oncology. 29:1013-1013
1013 Background: A high incidence of contralateral breast cancer has been reported in patients with BRCA1or BRCA2 mutations while the risk in patients with familial non-BRCA-associated breast cancer remains unclear. This study was undertaken to estim