Zobrazeno 241 - 250
of 522
pro vyhledávání: '"11"'
Autor:
Sui Shen, Linda A. Kroger, Jerry P. Lewis, Gerald L. DeNardo, John P. McGahan, Qansy Salako, Sally J. DeNardo, Desiree S. Goldstein, Norman B. Levy, Kathleen R. Lamborn
Publikováno v:
Journal of Clinical Oncology. 16:3246-3256
PURPOSE Lym-1, a monoclonal antibody that preferentially targets malignant lymphocytes, has induced remissions in patients with non-Hodgkin's lymphoma (NHL) when labeled with iodine 131 ((131)I). Based on the strategy of fractionating the total dose,
Autor:
M Mahjoubi, Marc Bonnay, G. Bastian, C. Cote, R. Hagipantelli, Dominique Mignard, Esteban Cvitkovic, Patrice Herait, Gilles Vassal, J. L. Misset, F. Saliba
Publikováno v:
Journal of Clinical Oncology. 16:2745-2751
PURPOSE Irinotecan (CPT-11), a camptothecin derivative, has shown efficacy against colorectal cancer. Delayed-onset diarrhea is its main limiting toxicity. The aim of this study was to determine the pathophysiology of CPT-11-induced delayed-onset dia
Autor:
T. De Pas, C Marone, M Fontana, Rossella Graffeo, C Martinoni, Giulia Zampino, Marco Colleoni, F Beretta, G Cipolla, A Gallino, A. Goldhirsch, Giovanni Martinelli
Publikováno v:
Scopus-Elsevier
PURPOSE Malignant pericardial effusion, although highly variable, is an uncommon complication of cancer. It is often associated with symptoms like dyspnea, chest pain, and cough, which may be severe and disabling. We analyzed the results of our curre
Autor:
Rebecca Gelman, Barbara Silver, Abram Recht, Bruce A. Bornstein, Judy Garber, J. Manola, James L. Connolly, Stella Hetelekidis, Jules E. Harris, Asa J. Nixon, Stuart J. Schnitt, E Chabner
Publikováno v:
Journal of Clinical Oncology. 16:2045-2051
PURPOSE To evaluate the safety and efficacy of breast-conserving therapy for young women with a family history (FH) suggestive of inherited breast cancer susceptibility. MATERIALS AND METHODS A total of 201 patients aged 36 or younger at diagnosis tr
Publikováno v:
Journal of Clinical Oncology. 16:1770-1776
PURPOSE To assess prospectively the accuracy of 2-[l8F]-2-deoxy-D-glucose positron emission tomography (FDG-PET) for predicting regional node involvement in cutaneous malignant melanoma (CMM). PATIENTS AND METHODS Twenty-three patients with CMM (prim
Publikováno v:
Journal of Clinical Oncology. 16:1916-1921
PURPOSE Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach (MLS) has recently been defined as a distinct clinicopathologic entity, often associated with Helicobacter pylori infection. Many regard antibiotic therapy as the primary treatm
Autor:
Joaquina Baranda, Brahma Konda, Kathleen D. Danenberg, Hartley Cohen, Dennis Salonga, Cynthia G. Leichman, Ralf Metzger, Peter V. Danenberg, Lawrence Leichman, K. Hayashi, Peter F. Crookes, Loren Laine, Heinz-Josef Lenz, Howard Silberman, Susan Groshen
Publikováno v:
Journal of Clinical Oncology. 16:309-316
PURPOSE We have previously shown that relative thymidylate synthase (TS) mRNA levels in primary gastric adenocarcinomas treated with fluorouracil (5-FU) and cisplatin are inversely associated with response and survival. This is a presumed function of
Autor:
P O Gunnarsson, B Persson, Bruce J. Giantonio, L Vitek, B Shannon, R Persson, Y Guedez, M Kotb, C. McAleer, T Kalland, M Dohlsten, Duane W. Newton, Louis M. Weiner, R K Alpaugh, Josephine Schultz
Publikováno v:
Journal of Clinical Oncology. 15:1994-2007
PURPOSE To establish the maximum-tolerated dose (MTD) and define the toxicities of a single-dose infusion of PNU-214565, a recombinant Escherichia coli-derived fusion protein of Staphylococcal enterotoxin A (SEA) and the Fab-fragment of the C242 mono
Autor:
Howard Safran, Alan G. Rosmarin, Kathy Radie-Keane, Hak Choy, Harold J. Wanebo, G. Cicchetti, E. Altenhein, Wallace Akerley, Paul J. Hesketh, Kirby I. Bland, T. P. King, F. Lopez, B. Wolf, William M. Sikov
Publikováno v:
Journal of Clinical Oncology. 15:901-907
PURPOSE To determine the maximum-tolerated dose (MTD), dose-limiting toxicities, and potential antitumor activity of weekly paclitaxel with concurrent radiation (RT) for locally advanced pancreatic and gastric cancer. PATIENTS AND METHODS Thirty-four
Publikováno v:
Scopus-Elsevier
PURPOSE This prospective phase II study was designed to test the activity and toxicity of a regimen of fluorouracil (5-FU) and cisplatin (CDDP) in combination with radiation therapy in the treatment of epidermoid cancer of the anal canal. PATIENTS AN