Zobrazeno 1 - 10
of 44
pro vyhledávání: ''
Autor:
Rohit Mehra, Emmanuel S. Antonarakis, Javed Siddiqui, Felix Y. Feng, Costantine Albany, Przemyslaw Twardowski, Bruce Montgomery, Yi-Mi Wu, Karen E. Knudsen, Maha Hussain, Young E. Whang, Mark N. Stein, Dan R. Robinson, Daniel H. Shevrin, Arul M. Chinnaiyan, Megan E.V. Caram, Lakshmi P. Kunju, Walter M. Stadler, Kathleen A. Cooney, Xuhong Cao, Stephanie Daignault-Newton, Robert J. Lonigro, Paul G. Corn, David Smith, Scott A. Tomlins
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 36, iss 10
Purpose To determine whether cotargeting poly (ADP-ribose) polymerase-1 plus androgen receptor is superior to androgen receptor inhibition in metastatic castration-resistant prostate cancer (mCRPC) and whether ETS fusions predict response. Patients a
Autor:
Peter Kamper, Alexander Lindholm d'Amore, David W. Scott, Joseph M. Connors, Randy D. Gascoyne, Marcel Nijland, Sohrab P. Shah, Christian Steidl, Anja Mottok, Anke van den Berg, Stephen Hamilton-Dutoit, Fong Chun Chan, Alina S. Gerrie, Kerry J. Savage, Maryse M. Power, Arjan Diepstra, Francesco d'Amore
Publikováno v:
Chan, F C, Mottok, A, Gerrie, A S, Power, M, Nijland, M, Diepstra, A, van den Berg, A, Kamper, P, d'Amore, F, d'Amore, A L, Hamilton-Dutoit, S, Savage, K J, Shah, S P, Connors, J M, Gascoyne, R D, Scott, D W & Steidl, C 2017, ' Prognostic Model to Predict Post-Autologous Stem-Cell Transplantation Outcomes in Classical Hodgkin Lymphoma ', Journal of Clinical Oncology, vol. 35, no. 32, pp. 3722-3733 . https://doi.org/10.1200/JCO.2017.72.7925
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 35(32), 3722-3733. AMER SOC CLINICAL ONCOLOGY
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 35(32), 3722-3733. AMER SOC CLINICAL ONCOLOGY
Purpose Our aim was to capture the biology of classical Hodgkin lymphoma (cHL) at the time of relapse and discover novel and robust biomarkers that predict outcomes after autologous stem-cell transplantation (ASCT). Materials and Methods We performed
Autor:
James H. Doroshow, DW Visscher, Matthew P. Goetz, Stephanie L. Safgren, Vera J. Suman, Andrew T. Ralya, Michael A. Mahr, Tufia C. Haddad, James N. Ingle, Benjamin R. Kipp, Jerry M. Collins, Joel M. Reid, Charles Erlichman, Zachary R. Chalmers, Garrett M. Frampton, Alex A. Adjei, John R. Hawse, Don W. Northfelt, Travis J. Dockter, Minetta C. Liu, Mary J. Kuffel, Sarah A. Buhrow, Matthew M. Ames, John L. Black, Howard Streicher, Renee M. McGovern
Publikováno v:
Journal of Clinical Oncology. 35:3391-3400
Purpose Endoxifen is a tamoxifen metabolite with potent antiestrogenic activity. Patients and Methods We performed a phase I study of oral Z-endoxifen to determine its toxicities, maximum tolerated dose (MTD), pharmacokinetics, and clinical activity.
Autor:
Paul G. Richardson, Hervé Avet-Loiseau, Benoit Dupas, Martine Escoffre-Barbe, Aurore Perrot, Eric Frampas, Caroline Bodet-Milin, Lotfi Benboubker, Michel Attal, Thierry Facon, Gerald Marit, Jean-Richard Eveillard, Florence Caillon, Cyrille Hulin, Véronique Dorvaux, Lionel Karlin, Carine Chaleteix, Denis Caillot, Anne-Marie Stoppa, Brigitte Pegourie, Philippe Moreau, Kamel Laribi, Laurent Garderet, Jean-Michel Nguyen, Nikhil C. Munshi, Kenneth C. Anderson, Aurélie Gaultier, Margaret Macro, Françoise Kraeber-Bodéré
Publikováno v:
Journal of Clinical Oncology. 35:2911-2918
Purpose Magnetic resonance imaging (MRI) and positron emission tomography–computed tomography (PET-CT) are important imaging techniques in multiple myeloma (MM). We conducted a prospective trial in patients with MM aimed at comparing MRI and PET-CT
Autor:
Stephanie Harmon, Glenn Liu, William L. Dahut, Timothy Perk, Robert Jeraj, Christie Lin, Jens Eickhoff, Andrea B. Apolo, Steven M. Larson, John L. Humm, Peter L. Choyke, Michael J. Morris
Publikováno v:
Journal of Clinical Oncology. 35:2829-2837
Purpose [18F]Sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) is a promising radiotracer for quantitative assessment of bone metastases. This study assesses changes in early NaF PET/CT response measures in metastatic
Autor:
Charles A. Powell
Publikováno v:
Journal of Clinical Oncology. 35:705-708
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and
Autor:
J. Jack Lee, Lixia Diao, John V. Heymach, Ferdinandos Skoulidis, Sanjay Gupta, Ximing Tang, Waun Ki Hong, Kevin R. Coombes, David J. Mauro, Ignacio I. Wistuba, Vassiliki A. Papadimitrakopoulou, Vincent A. Miller, Ja Seok Koo, Caimiao Wei, Eric H. Rubin, Julie G. Izzo, Li Shen, Scott N. Gettinger, Anne S. Tsao, Neda Kalhor, Jing Wang, Lauren Averett Byers, S. Andrew Peng, Alda L. Tam, Don L. Gibbons, Frank V. Fossella, Sarah B. Goldberg, Roy S. Herbst
Publikováno v:
Journal of Clinical Oncology. 34:3638-3647
Purpose By applying the principles of real-time biopsy, biomarker-based, adaptively randomized studies in non–small-cell lung cancer (NSCLC) established by the Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE)
Autor:
Shreyaskumar Patel, Binsheng Zhao, Vadim S. Koshkin, Laurence H. Baker, Denise K. Reinke, Lawrence H. Schwartz, Vanessa Bolejack, Scott M. Schuetze, Rashmi Chugh, Richard L. Wahl, Joo Hyun O
Publikováno v:
Journal of Clinical Oncology. 34:3680-3685
Purpose Despite the rapidly increasing use of [18F]fluorodeoxyglucose (FDG) –positron emission tomography (PET), the comparison of anatomic and functional imaging in the assessment of clinical outcomes has been lacking. In addition, there has not b
Autor:
Kevin R. Krull, Tara M. Brinkman, Wei Liu, Cara Kimberg, Yin Ting Cheung, Melissa M. Hudson, Slim Fellah, Deokumar Srivastava, Wilburn E. Reddick, Leslie L. Robison, Robert J. Ogg, Ching-Hon Pui
Publikováno v:
Journal of Clinical Oncology. 34:2644-2653
Purpose To examine associations among methotrexate pharmacodynamics, neuroimaging, and neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia treated on a contemporary chemotherapy-only protocol. Patients and Methods
Autor:
Andrew M. Evens, Erik Mittra, Mary Jo Lechowicz, Randy D. Gascoyne, Richard I. Fisher, John W. Sweetenham, Craig H. Moskowitz, Heiko Schöder, Bruce D. Cheson, John P. Leonard, Hongli Li, Eric D. Hsi, Brad S. Kahl, Lisa M. Rimsza, Jonathan W. Friedberg, James R. Cook, Michael LeBlanc, Michelle A. Fanale, Oliver W. Press, Ariela Noy, Nancy L. Bartlett, Michael V. Knopp, David J. Straus, Paul M. Barr, Ann S. LaCasce
Publikováno v:
Journal of Clinical Oncology. 34:2020-2027
Purpose Four US National Clinical Trials Network components (Southwest Oncology Group, Cancer and Leukemia Group B/Alliance, Eastern Cooperative Oncology Group, and the AIDS Malignancy Consortium) conducted a phase II Intergroup clinical trial that u