Zobrazeno 1 - 7
of 7
pro vyhledávání: ''
Autor:
Rohit Mehra, Emmanuel S. Antonarakis, Javed Siddiqui, Felix Y. Feng, Costantine Albany, Przemyslaw Twardowski, Bruce Montgomery, Yi-Mi Wu, Karen E. Knudsen, Maha Hussain, Young E. Whang, Mark N. Stein, Dan R. Robinson, Daniel H. Shevrin, Arul M. Chinnaiyan, Megan E.V. Caram, Lakshmi P. Kunju, Walter M. Stadler, Kathleen A. Cooney, Xuhong Cao, Stephanie Daignault-Newton, Robert J. Lonigro, Paul G. Corn, David Smith, Scott A. Tomlins
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 36, iss 10
Purpose To determine whether cotargeting poly (ADP-ribose) polymerase-1 plus androgen receptor is superior to androgen receptor inhibition in metastatic castration-resistant prostate cancer (mCRPC) and whether ETS fusions predict response. Patients a
Autor:
Peter Kamper, Alexander Lindholm d'Amore, David W. Scott, Joseph M. Connors, Randy D. Gascoyne, Marcel Nijland, Sohrab P. Shah, Christian Steidl, Anja Mottok, Anke van den Berg, Stephen Hamilton-Dutoit, Fong Chun Chan, Alina S. Gerrie, Kerry J. Savage, Maryse M. Power, Arjan Diepstra, Francesco d'Amore
Publikováno v:
Chan, F C, Mottok, A, Gerrie, A S, Power, M, Nijland, M, Diepstra, A, van den Berg, A, Kamper, P, d'Amore, F, d'Amore, A L, Hamilton-Dutoit, S, Savage, K J, Shah, S P, Connors, J M, Gascoyne, R D, Scott, D W & Steidl, C 2017, ' Prognostic Model to Predict Post-Autologous Stem-Cell Transplantation Outcomes in Classical Hodgkin Lymphoma ', Journal of Clinical Oncology, vol. 35, no. 32, pp. 3722-3733 . https://doi.org/10.1200/JCO.2017.72.7925
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 35(32), 3722-3733. AMER SOC CLINICAL ONCOLOGY
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 35(32), 3722-3733. AMER SOC CLINICAL ONCOLOGY
Purpose Our aim was to capture the biology of classical Hodgkin lymphoma (cHL) at the time of relapse and discover novel and robust biomarkers that predict outcomes after autologous stem-cell transplantation (ASCT). Materials and Methods We performed
Autor:
James H. Doroshow, DW Visscher, Matthew P. Goetz, Stephanie L. Safgren, Vera J. Suman, Andrew T. Ralya, Michael A. Mahr, Tufia C. Haddad, James N. Ingle, Benjamin R. Kipp, Jerry M. Collins, Joel M. Reid, Charles Erlichman, Zachary R. Chalmers, Garrett M. Frampton, Alex A. Adjei, John R. Hawse, Don W. Northfelt, Travis J. Dockter, Minetta C. Liu, Mary J. Kuffel, Sarah A. Buhrow, Matthew M. Ames, John L. Black, Howard Streicher, Renee M. McGovern
Publikováno v:
Journal of Clinical Oncology. 35:3391-3400
Purpose Endoxifen is a tamoxifen metabolite with potent antiestrogenic activity. Patients and Methods We performed a phase I study of oral Z-endoxifen to determine its toxicities, maximum tolerated dose (MTD), pharmacokinetics, and clinical activity.
Autor:
Stephanie Harmon, Glenn Liu, William L. Dahut, Timothy Perk, Robert Jeraj, Christie Lin, Jens Eickhoff, Andrea B. Apolo, Steven M. Larson, John L. Humm, Peter L. Choyke, Michael J. Morris
Publikováno v:
Journal of Clinical Oncology. 35:2829-2837
Purpose [18F]Sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) is a promising radiotracer for quantitative assessment of bone metastases. This study assesses changes in early NaF PET/CT response measures in metastatic
Autor:
Jeffrey E. Gershenwald, Charles R. Scoggins, Kelly M. McMasters, Peter D. Beitsch, B. Scott Davidson, Douglas S. Reintgen, Michael J. Edwards, Arnold J. Stromberg, James S. Goydos, Michael E. Egger, Marshall M. Urist, Stephan Ariyan, Jeffrey J. Sussman, Merrick I. Ross, Lee Hagendoorn, Robert C.G. Martin, R. Dirk Noyes
Publikováno v:
Journal of Clinical Oncology. 34:1079-1086
Purpose The Sunbelt Melanoma Trial is a prospective randomized trial evaluating the role of high-dose interferon alfa-2b therapy (HDI) or completion lymph node dissection (CLND) for patients with melanoma staged by sentinel lymph node (SLN) biopsy. P
Publikováno v:
Journal of Clinical Oncology. 35:261-261
261 Background: Tumor metabolism measured by [18F] fluorodeoxy-D-glucose (18F-FDG) positron emission tomography (PET) has a diagnostic and prognostic role in several cancers. The clinical implication of tumor metabolism in biliary tract cancer (BTC)
Autor:
Heather Homer, Ranjana H. Advani, Sarah E. Daadi, Margaret A. Shipp, Robert A. Redd, Richard T. Hoppe, Daphne de Jong, Gordon J. Freeman, Margaretha G.M. Roemer, Heather Sun, Yasodha Natkunam, Donna Neuberg, Bjoern Chapuy, Courtney Connelly, Azra H. Ligon, Philippe Armand, Scott J. Rodig
Publikováno v:
Journal of Clinical Oncology, 34(23), 2690-+. American Society of Clinical Oncology
Roemer, M G M, Advani, R H, Ligon, A H, Natkunam, Y, Redd, R A, Homer, H, Connelly, C F, Sun, H H, Daadi, S E, Freeman, G J, Armand, P, Chapuy, B, de Jong, D, Hoppe, R T, Neuberg, D S, Rodig, S J & Shipp, M A 2016, ' PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome ', Journal of Clinical Oncology, vol. 34, no. 23, pp. 2690-+ . https://doi.org/10.1200/JCO.2016.66.4482
Roemer, M G M, Advani, R H, Ligon, A H, Natkunam, Y, Redd, R A, Homer, H, Connelly, C F, Sun, H H, Daadi, S E, Freeman, G J, Armand, P, Chapuy, B, de Jong, D, Hoppe, R T, Neuberg, D S, Rodig, S J & Shipp, M A 2016, ' PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome ', Journal of Clinical Oncology, vol. 34, no. 23, pp. 2690-+ . https://doi.org/10.1200/JCO.2016.66.4482
Purpose Classical Hodgkin lymphomas (cHLs) include small numbers of malignant Reed-Sternberg cells within an extensive but ineffective inflammatory/immune cell infiltrate. In cHL, chromosome 9p24.1/PD-L1/PD-L2 alterations increase the abundance of th