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pro vyhledávání: '"Enrique Zudaire"'
Autor:
Xiaoyan M. Zhang, Enrique Zudaire, Brad St. Croix, Karen Morris, Jennifer Hwang, Dean Welsch, Guojun Yu, James M. Dunleavey, Yang Feng, Steven Seaman, Diana C. Haines, Decrescenzo Gary A, Saurabh Saha, Kuo Sheng Hsu, Zhongyu Zhu, Mary Beth Hilton, Christopher S. Szot, Dimiter S. Dimitrov, Deborah A. Swing, Yanping Wang, Amit Chaudhary, Holly Morris
Publikováno v:
Journal of Clinical Investigation. 128:2927-2943
Although nonmalignant stromal cells facilitate tumor growth and can occupy up to 90% of a solid tumor mass, better strategies to exploit these cells for improved cancer therapy are needed. Here, we describe a potent MMAE-linked antibody-drug conjugat