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Publikováno v:
Journal of Child Neurology. 36:281-287
Background: Rufinamide, a triazole derivative, is a new-generation antiseizure medication with a novel mechanism of action. We evaluated the efficacy and safety of rufinamide treatment in children with epilepsy younger than 4 years at our center. Met
Autor:
Peter W. Glynn, Satyanarayana Gedela, Anup D. Patel, Sravya Gedela, Daniel A. Freedman, Ann Salvator
Publikováno v:
Journal of Child Neurology. 34:735-738
Clobazam is a commonly used long-acting benzodiazepine approved by the US Food and Drug Administration (FDA) to treat seizures associated with Lennox Gastaut syndrome. The FDA approved maximum dosage of clobazam is 1 mg/kg/d or a total of 40 mg a day
Autor:
Kamil Detyniecki, Lawrence J. Hirsch, Richard Buchsbaum Bs, Jennifer Bonito Bs, Kenneth Kato Bs, Qianyu Wang Ba, Hyunmi Choi, Rafal D. Mazur
Publikováno v:
Journal of Child Neurology. 34:593-597
The main objective of this study was to assess the efficacy, safety, and retention rates of levetiracetam monotherapy in children with epilepsy. A retrospective review of pediatric patients receiving levetiracetam monotherapy at 2 large tertiary epil
Publikováno v:
Journal of Child Neurology. 34:94-98
Background: Levetiracetam is prescribed for a broad spectrum of seizure types but does not have a specific indication for absence epilepsy. We hypothesized that levetiracetam is commonly prescribed for children with absence epilepsies and evaluated t
Publikováno v:
Journal of Child Neurology. 33:519-524
Vigabatrin is recommended as first-line treatment for infantile spasms in tuberous sclerosis complex (TSC), but other indications in children with tuberous sclerosis complex are less known. We retrospectively reviewed 201 children with tuberous scler
Publikováno v:
Journal of Child Neurology. 33:153-157
Neonatal seizures are treated with phenobarbital and prolonged treatment does not prevent postneonatal epilepsy. The authors documented factors influencing phenobarbital use and determined whether published data changed practice. A total of 83 neonat
Publikováno v:
Journal of Child Neurology. 32:210-214
The objective of this study was to determine the efficacy and safety of levetiracetam in treatment of neonatal seizures due to hypoxic ischemic encephalopathy. Seizures often persist in neonates with hypoxic ischemic encephalopathy despite phenobarbi
Autor:
Nuran Salman, Güntülü Şık, Murat Sütçü, Ali Agacfidan, Edibe Pembegül Yıldız, Selda Hançerli Törün, Ayper Somer, Burak Tatlı, Agop Çıtak, Hacer Aktürk
Publikováno v:
Journal of Child Neurology. 31:345-350
Post-herpes simplex virus encephalitis relapses have been recently associated with autoimmunity driven by autoantibodies against N-methyl-d-aspartate (NMDA) receptors. Because it offers different treatment options, determination of this condition is
Publikováno v:
Journal of Child Neurology. 30:527-531
This retrospective study examined the efficacy and safety of zonisamide for Thai children and adolescents with intractable seizures. The medical records of 24 patients (13 male, 11 female), aged 2 to 18 years (median 11.5, mean 10.4) who received zon
Autor:
Karen Margallo, Julia Lockhart, Nancy Goldie, Adrienne Harvey, Ronit Mesterman, Jenny McEwen-Hill, Jan Willem Gorter
Publikováno v:
Journal of Child Neurology. 29:210-213
This retrospective cohort study reviewed set goals and their outcomes of children and adolescents with severe cerebral palsy who received botulinum toxin A in 2008 and 2009. Sixty children (36 male, mean age 9 years) were included. They received on a