Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Yong J. Lee"'
Autor:
Jin Hong Kim, Abdo J. Najy, Jian Li, Xu Luo, Hyeong‐Reh C. Kim, Mohammad Haroon Asif Choudry, Yong J. Lee
Publikováno v:
Journal of Cellular Physiology. 237:4180-4196
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor-mediated extrinsic apoptosis, specifically in cancer cells, and Bid (BH3-interacting domain death agonist) plays an important role in TRAIL-induced apoptosis. Ferr
Autor:
Yong Seok Park, Kalishwaralal Kalimuthu, Yong J. Lee, Ja Lok Ku, Jin Hong Kim, Xu Luo, Lin Zhang, M. Haroon A. Choudry
Publikováno v:
Journal of Cellular Physiology. 236:6666-6677
Abnormalities of the tumor vasculature result in insufficient blood supply and development of a tumor microenvironment that is characterized by low glucose concentrations, low extracellular pH, and low oxygen tensions. We previously reported that glu
Autor:
Hima Makala, Kalishwaralal Kalimuthu, Young Sun Lee, Yong Seok Park, Yong J. Lee, Simon C. Watkins, Yong Tae Kwon, M. Haroon A. Choudry, David L. Bartlett
Publikováno v:
J Cell Physiol
Ferroptosis has been reported as a unique form of cell death. However, in recent years, researchers have increasingly challenged the uniqueness of ferroptosis compared to other types of cell death. In this study, we examined whether ferroptosis share
Autor:
Mi Young Han, Sun Hee Baek, Eun Mi Park, Young Mee Park, Jin Na Min, Yong J. Lee, Yun Sil Lee
Publikováno v:
Journal of Cellular Physiology. 183:100-107
Expression of heat shock proteins (HSPs) has been shown to protect mammalian cells exposed to a variety of stress stimuli. Among various HSPs, small HSPs from diverse species were shown to protect cells against oxidative stress. Here, we show that th
Publikováno v:
Journal of Cellular Physiology. 174:27-34
Previously we and others have demonstrated that oxidative stress involving generation of reactive oxygen species (ROS) is responsible for the cytotoxic action of TNF alpha. Protective effect of small heat shock proteins (HSP) against diverse oxidativ
Thermotolerance expression in mitotic CHO cells without increased translation of heat shock proteins
Autor:
Michael J. Borrelli, Diane M. Stafford, Peter M. Corry, Yong J. Lee, Lisa A. Karczewski, Cynthia M. Rausch
Publikováno v:
Journal of Cellular Physiology. 169:420-428
The objective of this study was to unequivocally demonstrate thermotolerance expression in mammalian cells in the absence of stress-induced synthesis of heat shock proteins (HSPs). Mitotic cells were selected as an experimental system since their gen
Publikováno v:
Journal of Cellular Physiology. 167:369-379
An excellent correlation has been established between the quantity of protein associated with nuclei isolated from heat-shocked cells and the level of hyperthermic cell killing. However, controversy remains about whether increases in nuclear-associat
Publikováno v:
Journal of Cellular Physiology. 153:353-361
The constitutive HSP70 purified from CHO cells, which indicated a single band in SDS-polyacrylamide gel electrophoresis, showed multiple bands in native-polyacrylamide gel electrophoresis. These results indicate that the protein may exist in oligomer
Publikováno v:
Journal of Cellular Physiology. 152:118-125
We investigated the correlation between the development of acute thermotolerance and the phosphorylation, synthesis, and expression of the HSP28 family in murine L929 cells. Following heating at 43 degrees C for 30 min, thermotolerance developed rapi
Publikováno v:
Journal of Cellular Physiology. 150:441-446
We investigated a correlation between development of thermotolerance and expression, synthesis, or phosphorylation of HSP28 family in CHO plateau phase cells. After heating at 45.5 degrees C for 10 min, thermotolerance developed rapidly and reached i